Results 91 to 100 of about 3,598,435 (367)

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

Advanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin, Sheng‐Jia Lin, Yu Zhang, Kevin Huang, Cassidy Petree, Kevin Boyd, Pratishtha Varshney, Gaurav K. Varshney   +7 more
wiley   +1 more source

Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice

Cell Death Discovery
The Fscn2 (Fascin2) gene encodes an actin cross-linking protein that is involved in the formation of hair cell stereocilia and retina structure. Mutations in Fscn2 gene have been linked to hearing impairment and retinal degeneration in humans and mice ...
Rongrong Liu, Wenjing Shang, Yingying Liu, Yi Xie, Jun Luan, Ting Zhang, Ying Ma, Zengxian Wang, Yan Sun, Xicheng Song, Fengchan Han   +10 more
doaj   +1 more source

Emerging pharmacotherapy of tinnitus [PDF]

, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen, Azevedo AA, Bahmad FM, Berthold Langguth, Busto U, Courtney KR, Domeisen H, Feder R, Gananca MM, Goebel G, Goodnick PJ, Gresser U, Guitton MJ, Guitton MJ, Hastak SM, Henry JA, Hilton M, Holstein N, House JW, Kuchar DL, Langguth B, Lenarz T, Mahadevan S, Mardini MK, McCabe BF, Melcher JR, Moller AR, Moller AR, Newman CW, Oliver D, Podoshin L, Richard Salvi, Rogawski MA, Roth SH, Schlee W, Shambaugh GE, Shea JJ, Shulman A, Sieghart W, Tandon R, Wei BPC, Williams SH, Willow M, Zapp JJ   +43 more
core   +1 more source

Artificial Nervous Systems

Advanced Science, EarlyView.
By drawing inspiration from biological neural hierarchies and the working mechanisms of plasticity, researchers have constructed a series of bionic devices, including sensory devices, synapse devices, and artificial neural systems. They committed to simulating and surpassing the biological information processing function, thereby realizing the ...
Lu Yang, Qingwen Cheng, Yue Li, Ning Wu, Zhipeng Xu, Wentao Xu   +5 more
wiley   +1 more source

Pathways to Economic Outcomes and the Impact of Health: Comparing Hispanic and Non-Hispanic Adults after Foster Care [PDF]

, 2019
This study examines the financial outcomes in adulthood of Hispanics (N = 87) and White (Non-Hispanic, N = 498) persons placed in foster care during childhood. It uses the Casey Family Programs National Alumni Study (CFPNAS) database.
Alzate, Mónica M, Ph.D., LCSW, O\u27Brien, Kirk, Ph.D, Pecora, Peter J., Ph.D., Rosenthal, James A, Ph.D., Villegas, Susy, Ph.D., LCSW   +4 more
core   +1 more source

WHO Ear and Hearing Disorders Survey: Ecuador National Study 2008-2009

, 2014
Objectives. (1) Provide regional governments, institutions, and professionals with local and accurate information on the prevalence of ear and hearing disorders in the Ecuadorian population.
Alejandra Ullauri, Andrew Smith, M. Espinel, C. Jiménez, C. Salazar, R. Castrillon   +5 more
semanticscholar   +1 more source

Intelligent Supportive System for People with Profound Intellectual and Multiple Disabilities

Advanced Intelligent Systems, EarlyView.
A holistic INSENSION system is developed—a novel intelligent decision support system leveraging state‐of‐the‐art noninvasive audio‐visual sensor technologies together with machine learning algorithms and expert knowledge, to detect and interpret behaviors and communications (nonverbal signals—NVSs) of people with PIMD in challenging real‐world ...
Gašper Slapničar, Michał Kosiedowski, Arkadiusz Radziuk, Erik Dovgan, Torsten Hammann, Meike Engelhardt, Christin Kupitz, Carmen Campomanes‐Alvarez, Dorota Janczewska, Peter Zentel, Mitja Luštrek   +10 more
wiley   +1 more source

A survey of services for the speech and hearing handicapped in New England [PDF]

, 1950
Thesis (Ed.
Campbell, Marion Margaret, Dunbar, Alice Louise, Farquhar, Mary Stuart, Foster, Honora B., Kiley, Mary Claire, Roberts, Rosalie Ackley, Weinberg, Robert E.   +6 more
core   +2 more sources

Investigating the Effect of Physical Activities on Social Skills in Athletes and Non-athletes Deaf and Hard of Hearing Students [PDF]

Journal of Pediatrics Review
Background: Hearing loss and deafness can significantly impact the socialization process, potentially leading to developmental delays, communication challenges, and difficulties in forming social relationships.
Fatemeh Eghbalian, Amir Bahariani, Roya Najafi-vosogh, Homa Naderifar   +3 more
doaj  

Survey of hearing disorders in an urban population in Rondonia, Northern Brazil.

Revista de Saúde Pública, 2013
OBJECTIVE To identify the prevalence of hearing loss for the population in the urban area. METHODS A cross-sectional household survey based on the World Health Organization Ear and Hearing Disorders Survey Protocol was conducted in 298 households in ...
M. Bevilacqua, M. R. Banhara, Ariádnes Nóbrega de Oliveira, A. L. M. Moret, K. F. Alvarenga, M. Caldana, L. Camargo, O. A. Costa, J. R. Bastos   +8 more
semanticscholar   +1 more source