Results 81 to 90 of about 444,058 (336)

Neuroprotective Effects of Curcumin on the Proliferation and Viability of Neural Stem Cells against H2O2

open access: yesOtorhinolaryngology and Facial Plastic Surgery, 2019
Background: Oxidative stress and neuroinflammation have found to be implicated in several neurodegenerative disorders (ND). Neuroprotection against oxidative agents has been proposed as a therapy on the basis that it might prevent neuroinflammation ...
Maryam Sadat Khoramgah   +7 more
doaj   +1 more source

Measuring and understanding patterns of change in intervention studies with children: implications for evidence-based practice [PDF]

open access: yes, 2007
Purpose: Comparisons across studies of the effects of intervention are problematic. Such analyses raise both methodological and statistical challenges.
Dockrell, Julie, Law, James
core   +2 more sources

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

open access: yesAdvanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun   +15 more
wiley   +1 more source

Gene Therapy in Hearing Loss Treatment: A Review

open access: yesOtorhinolaryngology and Facial Plastic Surgery, 2020
Background Hearing loss, which is highly heterogeneous, is the most common sensorineural disorder in humans. More than 50% of the causes of deafness are attributed to genetic factors.
Atefeh Shirazi Tehrani   +3 more
doaj   +1 more source

Pathways to Economic Outcomes and the Impact of Health: Comparing Hispanic and Non-Hispanic Adults after Foster Care [PDF]

open access: yes, 2019
This study examines the financial outcomes in adulthood of Hispanics (N = 87) and White (Non-Hispanic, N = 498) persons placed in foster care during childhood. It uses the Casey Family Programs National Alumni Study (CFPNAS) database.
Alzate, Mónica M, Ph.D., LCSW   +4 more
core   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Disabilities in the Writing Center [PDF]

open access: yes, 2015
Since writing centers serve communities of teachers and learners, they will inevitably serve people with disabilities. Ever since the 1980s, writing center workers have explored the issue of tutoring students with disabilities, people who may require ...
Babcock, Rebecca Day
core   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

open access: yesAdvanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot   +2 more
wiley   +1 more source

Ribbon Synapse Reformation: A Key Role for the Hearing Restoration; A Review

open access: yesOtorhinolaryngology and Facial Plastic Surgery, 2019
Background: Auditory sensory epithelium of mammals has two types of mechanosensory cells including the inner hair cells (IHC) and outer hair cells (OHC). IHC in the mammalian inner ear is an important component for the sound perception.
Somayeh Niknazar   +3 more
doaj   +1 more source

Features of teaching students with motor skills disorder caused by hearing loss [PDF]

open access: diamond, 2021
Elena Mamedova   +2 more
openalex   +1 more source

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