Results 71 to 80 of about 3,033,166 (245)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Congenital hearing loss in Malta : a survey [PDF]

, 1990
The congenitally deaf infant who acquires deafness prior to development of language present special problems when compared to other hearing impaired individuals.
Pace Balzan, Jacqueline, Saliba, F., Degiorgio, Raymond, Fenech, Anthony G.   +3 more
core  

Congenital conductive hearing loss in dyschondrosteosis.

, 2003
Conductive hearing loss was detected in a boy with a previous diagnosis of dyschondrosteosis. Dyschondrosteosis is a rare inherited condition characterized by mesomelic dwarfism and Madelung's deformity.
Oudesluijs, G.G., Cremers, C.W.R.J., Sengers, R.C.A., Leenheer, E. de, Rappold, G.A., Kuijpers-Jagtman, A.M.   +5 more
core   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Medico-Legal Aspects of Traumatic Ear Injuries and the Resulting Permanent Infirmities in Assiut University Hospitals [PDF]

Egyptian Society of Clinical Toxicology Journal
Background: Post traumatic hearing loss has a great impact on the quality of life of individuals. Aim of the work: This study was done to identify the clinical and forensic aspects of ear injuries and their sequelae.
Doaa Almaz, Shimaa Mohammed, Maha Aly, Asmaa soliman   +3 more
doaj   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Prevalence of hearing loss among patients attending the private otolaryngology clinic, Ramadi city, Anbar, Iraq

The Egyptian Journal of Otolaryngology
Background Hearing loss is a common problem worldwide with a global prevalence of 20%. There is no local relevant study from Iraq about the prevalence of hearing loss.
Raid M. Al-Ani, Karrar Khalid Jamal, Fatima Wadhah Fakhri, Sabaa Haitham Muhamed, Nabaa Haitham Muhamed, Omar Fadhil Ali   +5 more
doaj   +1 more source

Reliability of auditory steady-state response to bone conduction stimuli in assessing hearing loss in children

The Egyptian Journal of Otolaryngology, 2016
En Abstract Objective This study was designed to investigate bone Conduction (BC)/auditory steady state response (ASSR) in children with normal hearing, together with various types of hearing loss, to find out an objective method to differentiate between
Naema Ismaila, Elham El-Saiid, Amal El Sebaii, Hanaa Fadel   +3 more
doaj   +1 more source

Brain Network Dynamics of Local and Global Predictive Processing in Aging

Advanced Science, EarlyView.
Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen, Gemma Fernández‐Rubio, David R. Quiroga‐Martinez, Mattia Rosso, Mathias Klarlund, Kit Melissa Larsen, Hartwig Roman Siebner, Morten L. Kringelbach, Peter Vuust, Leonardo Bonetti   +9 more
wiley   +1 more source

Audiological Manifestations in Kabuki (Niikawa-Kuroki) Syndrome

Philippine Journal of Otolaryngology Head and Neck Surgery, 2011
Objective: To describe the audiological profile, clinical features and briefly summarize the speech and language development of a child with Kabuki syndrome (KS).
Celina Ann M. Tobias, Teresa Luisa Gloria-Cruz, Charlotte M. Chiong   +2 more
doaj   +1 more source