Results 31 to 40 of about 17,351 (240)

Audiometric profile of civilian pilots according to noise exposure

Revista de Saúde Pública, 2014
OBJECTIVE To evaluate the audiometric profile of civilian pilots according to the noise exposure level. METHODS This observational cross-sectional study evaluated 3,130 male civilian pilots aged between 17 and 59 years. These pilots were subjected to
Taiana Pacheco Falcão, Ronir Raggio Luiz, Gabriel Eduardo Schütz, Márcia Gomide da Silva Mello, Volney de Magalhães Câmara   +4 more
doaj   +1 more source

NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss

Frontiers in Cell and Developmental Biology, 2022
The reactive oxygen species (ROS)-generating NADPH oxidase NOX3 isoform is highly and specifically expressed in the inner ear. NOX3 is needed for normal vestibular development but NOX-derived ROS have also been implicated in the pathophysiology of ...
Francis Rousset, German Nacher-Soler, Vivianne Beatrix Christina Kokje, Vivianne Beatrix Christina Kokje, Stéphanie Sgroi, Marta Coelho, Karl-Heinz Krause, Pascal Senn, Pascal Senn   +8 more
doaj   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Application of Risk Estimation of Noise-induced Hearing Loss Method in Evaluations of Occupational Disease Hazards in Construction Projects in China [PDF]

Journal of Risk Analysis and Crisis Response (JRACR), 2016
To protect the workers exposed to industrial noise, prevent and control the occurrence of noise-induced hearing loss, and reduce the incidence of occupational noise-induced deafness, a method and its application example were presented to assess the risk ...
Minyan Li, Deyin Huang, Qian Zhang, Mao Liu   +3 more
doaj   +1 more source

Drug development for noise-induced hearing loss

Expert Opinion on Drug Discovery, 2020
Excessive exposure to noise is a common occurrence that contributes to approximately 50% of the non-genetic hearing loss cases. Researchers need to develop standardized preclinical models and identify molecular targets to effectively develop prevention and curative therapies.
Luis Lassaletta, Luis Lassaletta, Isabel Varela-Nieto, Miryam Calvino, Miryam Calvino, Rafael Cediel, Silvia Murillo-Cuesta   +6 more
openaire   +3 more sources

What is noise-induced hearing loss? [PDF]

British Journal of Hospital Medicine, 2019
Noise-induced hearing loss is sensory deafness caused by long-term exposure of the auditory system to a noisy environment. Auditory fatigue is an early symptom of noise-induced hearing loss, and hearing can gradually recover after people leave a noisy environment.
Tonghui Ding, Aihui Yan, Ke Liu
openaire   +3 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

Advanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu   +11 more
wiley   +1 more source

Elevator dynamic monitoring and early warning system based on machine learning algorithm

IET Networks, EarlyView., 2022
In order to monitor and warn the elevator dynamics, in this work, the machine learning algorithm is introduced, and the particle swarm algorithm is used to perfect the model. The model is optimised, and the experimental comparison shows that the optimisation of the model parameters can further improve the accuracy of the elevator load prediction. Then,
Shuai Zhang, Qiangguo Yin, Jinlong Wang
wiley   +1 more source

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source