Results 91 to 100 of about 172,130 (301)

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source

Acute kidney injury, secondary to valacyclovir use during pregnancy for the prevention of fetal cytomegalovirus infection

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract High dose valacyclovir treatment of pregnant women has become a common treatment for primary CMV infection, to prevent vertical transmission to the fetus. We present a case of a healthy young pregnant female with primary CMV infection during the first trimester who was diagnosed with acute kidney injury secondary to valacyclovir treatment ...
Jason Brafman, Yechiel Schlesinger, Moshe Barg, Shmuel Benenson   +3 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Nationwide epidemiological survey of idiopathic sudden sensorineural hearing loss in Japan

Acta Oto-Laryngologica, 2017
Objectives: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. Methods: The subjects for this analysis were patients registered in a Japanese multicentre database between ...
Ryosuke Kitoh, Shin-ya Nishio, K. Ogawa, S. Kanzaki, N. Hato, M. Sone, S. Fukuda, A. Hara, T. Ikezono, Kotaro Ishikawa, S. Iwasaki, K. Kaga, S. Kakehata, A. Matsubara, T. Matsunaga, T. Murata, Y. Naito, T. Nakagawa, K. Nishizaki, Y. Noguchi, H. Sano, Hiroaki Sato, Mikio Suzuki, H. Shojaku, Haruo Takahashi, H. Takeda, T. Tono, H. Yamashita, T. Yamasoba, S. Usami   +29 more
semanticscholar   +1 more source

Predicting cochlear structural alterations from auditory function in age‐related hearing loss mice based on optical coherence tomography

Journal of Intelligent Medicine, EarlyView.
Abstract With global population aging, age‐related hearing loss has become a major public health concern. Understanding the relationship between auditory functional decline and cochlear structural degeneration is essential for early detection and precise intervention.
Shu Zheng, Zhiqi Li, Junyue Wang, Guangjian Ni   +3 more
wiley   +1 more source

Is There a Role for Sodium Fluoride in Otosclerosis Treatment?

The Laryngoscope, EarlyView.
Various reports have investigated the role of NaF for stabilizing SNHL in the setting of otosclerosis; however, there currently remains no established practice guideline or widespread consensus. The purpose of this paper is to interpret the literature to determine best practices for the use of NaF in otosclerosis management.
Timothy Shim, Kevin Wong, Michael J. Ruckenstein   +2 more
wiley   +1 more source

Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance

The Laryngoscope, EarlyView.
In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi, Sylvain Bourdoncle, Jean Fanet, Stéphane Gargula, Denis Ayache, Loïc Duron, Julien Savatovsky, Guillaume Poillon   +7 more
wiley   +1 more source

The Auditory Steady-State Response and the Relationship between Electrophysiological and Behavioural Thresholds

Diagnostics
Background: This study examined the relationship between behavioural thresholds as measured by pure tone audiometry and electrophysiological thresholds measured by the Auditory Steady-State Response (ASSR) in children with normal hearing and ...
Cyntia Barbosa Laureano Luiz, Daniela Gil, Piotr Henryk Skarzynski, Magdalena Beata Skarżyńska, Milaine Dominici Sanfins, Marisa Frasson de Azevedo   +5 more
doaj   +1 more source

Evaluation of Cochlear Nerve Scale with MRI in Patients with Idiopathic Unilateral Sensorineural Hearing Loss

Sakarya Tıp Dergisi, 2019
Objective: The aim of this study was to evaluate the cochlear nerve diameter in patients with unilateral sensorineural hearing loss and to compare the diameter of the normal side with the hearing loss side.
Onur Taydaş, Hakkı Caner İnan
doaj   +1 more source

Childhood sensorineural hearing loss and adult mental health up to 43 years later: results from the HUNT study

BMC Public Health, 2019
Background Hearing loss is a global public health problem putting millions of people at risk of experiencing impediments in communication and potentially impaired mental health. Many studies in this field are based on small, cross sectional samples using
Mariann Idstad, Kristian Tambs, Lisa Aarhus, Bo Lars Engdahl   +3 more
doaj   +1 more source