Results 221 to 230 of about 149,128 (273)
Abstract Objective Spontaneous cerebrospinal fluid (sCSF) leaks of lateral skull base have little consensus on optimal management. We synthesized and evaluated current literature via systematic and meta‐analysis to compare the success rates and complications of the different surgical techniques for middle cranial fossa (MCF) sCSF leak repair.
Dimitrios Spinos+9 more
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier+26 more
wiley +1 more source
How exome sequencing improves the diagnostics and management of men with non‐syndromic infertility
Abstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Birgit Stallmeyer+2 more
wiley +1 more source
ABSTRACT Introduction Tympanic membrane perforation can cause hearing impairment with detrimental effects on communication and quality of life, and is a problem affecting an estimated 250 million people. To date, there is little analysis to inform public policy on options for assistive hearing technology rehabilitation in this group.
Thomas Hampton+3 more
wiley +1 more source
Abstract Inclusive development in the Global South encounters challenges from a growing disability and development gap amid increasing education, employment and social participation, accompanied by higher expectations and resource consumption. This study aims to analyse the spatio‐temporal disparity of the Index of Disability‐Related Multiple ...
Ning Qiu+3 more
wiley +1 more source
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Pediatric Clinics of North America, 1989
The authors emphasize the importance of early identification and early intervention concerning the management of children with Sensorineural Hearing Loss. The pediatrician plays a critical role in initiating the necessary clinical and audiological evaluations. Guidelines and treatment options are reviewed.
James S. Reilly, Stephen Epstein
openaire +3 more sources
The authors emphasize the importance of early identification and early intervention concerning the management of children with Sensorineural Hearing Loss. The pediatrician plays a critical role in initiating the necessary clinical and audiological evaluations. Guidelines and treatment options are reviewed.
James S. Reilly, Stephen Epstein
openaire +3 more sources
Autoimmune Sensorineural Hearing Loss [PDF]
The author proposes the existence of a new entity, autoimmune sensorineural hearing loss, on the basis of diagnostic study and treatment experience with a series of 18 patients. In each case the clinical pattern did not fit with known entities and thus seemed to merit distinctive categorization.
openaire +5 more sources
Sensorineural hearing loss in pseudoexfoliation
Canadian Journal of Ophthalmology, 2007Pseudoexfoliation (PEX), which affects anterior segment structures, is thought to be a systemic disorder. The purpose of this study was to determine the possible relation between PEX and sensorineural hearing loss.The study group included 51 patients with PEX and 22 controls without PEX.
Filiz Ozdemir+5 more
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Sensorineural hearing loss in neurobrucellosis
The Journal of Laryngology & Otology, 1993AbstractA case of neurobrucellosis presenting to the otologist with sensorineural hearing loss (SNHL) as the predominant clinical feature is reported. The diagnostic features and treatment options are discussed and the need for prolonged combination treatment to prevent relapse and further deterioration of hearing stressed. SNHL in neurobrucellosis has
Ratna Thomas+3 more
openaire +3 more sources