Results 151 to 160 of about 5,170,738 (411)

Interplay between Nutrition and Hearing Loss: State of Art

open access: yesNutrients, 2018
Hearing loss has been recently ranked as the fifth leading cause of years lived with disability, ahead of many other chronic diseases such as diabetes, dementia, or chronic obstructive pulmonary disease.
A. M. Puga   +3 more
semanticscholar   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Permanent Unilateral Hearing Loss (UHL) and Childhood Development

open access: yesCurrent Otorhinolaryngology Reports, 2018
Purpose of ReviewThe aim of this study is to summarize the consequences of permanent unilateral hearing loss (UHL) on the development of children as documented in the recent literature.Recent FindingsCongenital and early-identified UHL places young ...
J. Lieu
semanticscholar   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Prevalence of Hearing Loss by Severity in the United States.

open access: yesAmerican Journal of Public Health, 2016
OBJECTIVES To estimate the age- and severity-specific prevalence of hearing impairment in the United States. METHODS We conducted cross-sectional analyses of 2001 through 2010 data from the National Health and Nutrition Examination Survey on 9648 ...
A. Goman, F. Lin
semanticscholar   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

The impact of rehabilitation on quality of life after hearing loss: a systematic review

open access: yesEuropean Archives of Oto-Rhino-Laryngology, 2018
PurposeHearing loss is a major health problem and is associated with several negative outcomes such as difficulties in communicating and poor quality of life.
A. Brodie, Bethany Smith, J. Ray
semanticscholar   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

Roles of supporting cells in the maintenance and regeneration of the damaged inner ear: A literature review

open access: yesJournal of Otology
The inner ear sensory epithelium consists of two major types of cells: hair cells (HCs) and supporting cells (SCs). Critical functions of HCs in the perception of mechanical stimulation and mechanosensory transduction have long been elucidated.
Jing-Ying Guo   +3 more
doaj  

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