Results 71 to 80 of about 4,472,659 (361)

Performance Characteristics of Anti‐Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Background Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti‐collagen II (anti‐Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

Clinical and audiological profile of patients with sudden sensorineural hearing loss after exposure to recreational noise

Brazilian Journal of Otorhinolaryngology
According to the World Health Organization, significant hearing loss in young people exposed to recreational acoustic trauma has become a public health issue.
Lara Freire Bezerril Soares, Breno Lima de Almeida, Igor Ataíde Silva Teixeira, Maria Luisa Frechiani Lara Maciel, Jorge Vinícius Leocádio Monteiro, Luanna Miranda Martins, Marina Cançado Passarelli Scott, Norma de Oliveira Penido   +7 more
doaj   +1 more source

Self-Reported Hearing Loss in Older Adults Is Associated With Higher Emergency Department Visits and Medical Costs

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2019
Hearing loss is common among older adults. Thus, it was of interest to explore differences in health care utilization and costs associated with hearing loss and hearing aid use.
Timothy S. Wells PhD, Lizi Wu PhD, Gandhi R. Bhattarai PhD, Lorraine D. Nickels BSN, MS, Steven R. Rush MA, LP, Charlotte S. Yeh MD   +5 more
doaj   +1 more source

Frequency and clinical features of hearing loss caused by STRC deletions

Scientific Reports, 2019
Sensorineural hearing loss is a common deficit and mainly occurs due to genetic factors. Recently, copy number variants (CNVs) in the STRC gene have also been recognized as a major cause of genetic hearing loss.
Yoh Yokota, Hideaki Moteki, S. Nishio, Tomomi Yamaguchi, K. Wakui, Yumiko Kobayashi, K. Ohyama, Hiromitsu Miyazaki, R. Matsuoka, S. Abe, K. Kumakawa, Masahiro Takahashi, H. Sakaguchi, N. Uehara, T. Ishino, T. Kosho, Y. Fukushima, S. Usami   +17 more
semanticscholar   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Leveraging underrepresented population data improves interpretation of genetic variants associated with hearing loss

Scientific Reports
Hearing loss is genetically heterogeneous, with over 121 implicated genes. Minor allele frequency (MAF) data from population databases greatly aid variant interpretation; however, these databases are predominantly based on individuals of European ...
Sun Young Joo, Seung Hyun Jang, Jung Ah Kim, Se Jin Kim, Jae Young Choi, Jinsei Jung, Heon Yung Gee   +6 more
doaj   +1 more source

Hearing Loss With Congenital Cytomegalovirus Infection

Pediatrics, 2019
Incidence of hearing loss in children with cCMV infection is discussed, and risk indicators for hearing loss are described. OBJECTIVE: In this study, we determined the prevalence of hearing loss in 157 children with proven congenital cytomegalovirus ...
I. Foulon, Yannick De Brucker, R. Buyl, Elke Lichtert, K. Verbruggen, D. Piérard, Fleur A. Camfferman, L. Gucciardo, F. Gordts   +8 more
semanticscholar   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Systematic genetic assessment of hearing loss using whole-genome sequencing identifies pathogenic variants

Experimental and Molecular Medicine
Hearing loss is a clinically and genetically heterogeneous sensorineural disease that affects approximately 1 out of 1000 newborns. For the molecular diagnosis of genetic hearing loss, target panel or whole-exome sequencing (WES) have been widely used ...
Jung Ah Kim, Seung Hyun Jang, Sun Yung Joo, Se Jin Kim, Jae Young Choi, Jinsei Jung, Heon Yung Gee   +6 more
doaj   +1 more source

Outcomes of unilateral idiopathic sudden sensorineural hearing loss: Two decades of experience

Laryngoscope Investigative Otolaryngology, 2019
Objectives (a) Determine the demographic and medical risk factors for patients who presented with unilateral idiopathic sudden sensorineural hearing loss (ISSNHL); (b) identify treatments that patients underwent; (c) evaluate the adequacy of follow‐up ...
Yanjun Xie, Norman A. Orabi, Terry A. Zwolan, Gregory J. Basura   +3 more
doaj   +1 more source