Results 61 to 70 of about 4,375,853 (312)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Cohort profile: Netherlands Longitudinal Study on Hearing (NL-SH)

BMJ Open, 2023
Purpose The Netherlands Longitudinal Study on Hearing (NL-SH) was set up to examine associations of hearing ability with psychosocial, work and health outcomes in working age adults.Participants Inclusion started in 2006 and is ongoing.
Johannes R Anema, Sophia E Kramer, Mariska Stam, Birgit I Lissenberg-Witte, Cas Smits, Marieke F van Wier, Lotte A Jansen, Thadé Goderie, Janneke Nachtegaal, Johannes H M van Beek, Ulrike Lemke   +10 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Hearing Impairment and Visual Rehabilitation Outcomes

JAMA Ophthalmology
Importance Dual sensory impairment—that is, concurrent hearing and vision impairment—is common in aging populations. Individuals with dual sensory impairment face unique social and functional challenges, but the benefit of conventional rehabilitation in addressing these challenges is not well researched.
Obaideen, Anas, Goldstein, Judith E., Bradley, Chris, Massof, Robert W., Fujiwara, Kyoko, Ramulu, Pradeep Y., Xiong, Yingzi   +6 more
openaire   +2 more sources

Sensitivity to temporal fine structure and hearing-aid outcomes in older adults

Frontiers in Neuroscience, 2014
Objective: to investigate the effect of sensitivity to temporal fine structure on subjective measures of hearing aid outcome.Design: Prior to receiving hearing aids, participants completed a test to assess sensitivity to temporal fine structure (TFS ...
Elvira ePerez Vallejos, Abby eMccormack, Barrie eEdmonds   +2 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Coordination of gaze and speech in communication between children with hearing impairment and normal-hearing peers.

, 2014
To investigate gaze behavior during communication between children with hearing impairment (HI) and normal-hearing (NH ...
Hansson, Kristina,, Andersson, Richard,, Sahlén, Birgitta,, Sandgren, Olof,, van de Weijer, Joost,, Lund University., Sandgren, Olof, Andersson, Richard, van de Weijer, Joost, Hansson, Kristina, Sahlén, Birgitta   +10 more
core   +1 more source

Efficacy of Combined Hyperbaric Oxygen, per Os Steroid, and Prostaglandin E1 Therapy for Idiopathic Sudden Sensorineural Hearing Loss and Prognostic Factors for Recovery

Journal of Otorhinolaryngology, Hearing and Balance Medicine
Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is an abrupt unilateral hearing loss of unknown origin. Combination therapy with hyperbaric oxygen (HBO), systemic steroids (SS), and prostaglandin E1 (PGE1) has been used in Japan ...
Takumi Nakayama, Satoshi Hara, Takeshi Kusunoki, Yusuke Takata, Hirotomo Honma, Takashi Anzai, Yoshinobu Kidokoro, Akihisa Yoshikawa, Fumihiko Matsumoto   +8 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Relative Importance of Monaural Sound Deprivation and Bilateral Significant Hearing Loss in Predicting Cochlear Implantation Outcomes

, 2011
Objectives: Making evidence-based recommendations to prospective unilateral cochlear implant recipients on the potential benefits of implanting one or the other ear is challenging for cochlear implant teams.
Catherine M. McMahon, Lyxell, Björn,, Björn Lyxell, Geneviève Tremblay, Boisvert, Isabelle,, McMahon, Catherine M,, Isabelle Boisvert, Tremblay, Genevieve,   +7 more
core   +1 more source