Results 91 to 100 of about 13,663,771 (328)

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Estudo audiológico e genético de lactentes de alto risco Audiological and genetics studies in high-risk infants

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
A audição é um dos principais meios de contato do indivíduo com o mundo externo, desempenhando papel fundamental na integração com a sociedade. OBJETIVO: Analisar os resultados obtidos na avaliação audiológica, otorrinolaringológica e genética de ...
Maria Francisca Colella-Santos   +6 more
doaj   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Quality of life of children with poor school performance: association with hearing abilities and behavioral issues

open access: yesArquivos de Neuro-Psiquiatria
The aim of the present study was to investigate the quality of life of children with poor school performance and its association with behavioral aspects and hearing abilities. Methods: This cross-sectional observational study, developed in a town in the
Bárbara Antunes Rezende   +2 more
doaj   +1 more source

Headphone Evaluation for App-Based Automated Mobile Hearing Screening

open access: yesInternational Archives of Otorhinolaryngology, 2018
Introduction With the need for hearing screenings increasing across multiple populations, a need for automated options has been identified. This research seeks to evaluate the hardware requirements for automated hearing screenings using a mobile ...
Adam W. Pickens   +4 more
doaj   +1 more source

Hearing in Noise Test in Subjects With Conductive Hearing Loss

open access: yesJournal of the Formosan Medical Association, 2009
It has been reported that patients with pure conductive hearing loss (CHL) have remarked that their hearing is better in the presence of background noise. This study investigated the ability for speech discrimination under background noise in adult subjects with CHL, using the Mandarin Hearing in Noise Test (M-HINT).Seventeen subjects with unilateral ...
Kai-Nan Lin   +3 more
openaire   +4 more sources

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

open access: yesAdvanced Science, EarlyView.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang   +15 more
wiley   +1 more source

Temporal Resolution Ability in Students with Dyslexia and Reading and Writing Disorders

open access: yesInternational Archives of Otorhinolaryngology, 2014
Introduction The Gaps-in-Noise (GIN) test assesses the hearing ability of temporal resolution. The development of this ability can be considered essential for learning how to read.
Juliana Chaubet   +2 more
doaj   +1 more source

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