Results 101 to 110 of about 14,054,968 (363)

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

Hearing Loss in Infants with Microcephaly and Evidence of Congenital Zika Virus Infection - Brazil, November 2015-May 2016.

MMWR. Morbidity and mortality weekly report, 2016
Congenital infection with Zika virus causes microcephaly and other brain abnormalities (1). Hearing loss associated with other congenital viral infections is well described; however, little is known about hearing loss in infants with congenital Zika ...
M.C. Leal, L. Muniz, Tamires S A Ferreira, Cristiane M Santos, L. C. Almeida, V. van der Linden, R. Ramos, L. C. Rodrigues, Silvio S Caldas Neto   +8 more
semanticscholar   +1 more source

Effects of gestational and lactational exposure to low dose mercury chloride (HgCl2) on behaviour, learning and hearing thresholds in WAG/Rij rats [PDF]

We investigated the effects of inorganic mercury exposure during gestational/lactational periods on the behaviour, learning and hearing functions in a total of 32, 5-week-old and 5-month-old WAG/Rij rats (equally divided into 4 groups as 5-week and 5 ...
Ateş, Nurbay, Bayrak, Gunce, Beyaz, Sumeyye, Demir, Buse, Erdolu, Cem Onur, Kara, Ahmet, Karadenizli, Sabriye, Sahin, Deniz   +7 more
core   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Hubungan Gangguan Pendengaran Dengan Kemampuan Bahasa Pada Anak Sindrom Down [PDF]

, 2015
Background: Down syndrome is a genetic chromosomal disorder called trisomy. Patients with Down syndrome have an extra chromosome 21. This is because of non-disjunction or aneuploidy of the chromosomes.
Muhammad, A. R. (Arge), Purwanti, A. (Asri), Yunika, K. (Kanti)   +2 more
core   +3 more sources

Diffusion tensor imaging in children with unilateral hearing loss: A pilot study [PDF]

, 2014
Objective: Language acquisition was assumed to proceed normally in children with unilateral hearing loss (UHL) since they have one functioning ear. However, children with UHL score poorly on speech-language tests and have higher rates of educational ...
Coalson, Rebecca S, Lieu, Judith E.C., Rachakonda, Tara, Shimony, Joshua S   +3 more
core   +3 more sources

Triagem auditiva neonatal: ocorrência de falhas, perdas auditivas e indicadores de riscos Neonatal Hearing Screening: failures, hearing loss and risk indicators

Brazilian Journal of Otorhinolaryngology, 2011
Verificar o índice de falha, de perda auditiva e sua associação com variáveis demográficas e indicadores de risco para deficiência auditiva em recém-nascidos submetidos ao Programa de Triagem Auditiva Neonatal em um hospital secundário. MATERIAL E MÉTODO:
Raquel Mari Onoda, Marisa Frasson de Azevedo, Amélia Miyashiro Nunes dos Santos   +2 more
doaj   +1 more source

Polydopamine Nanohydrogel Decorated Adhesive and Responsive Hierarchical Microcarriers for Deafness Protection

Advanced Science, EarlyView.
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen, Hui Zhang, Jiayi Li, Xianmei Wei, Chenjie Yu, Yuanjin Zhao, Maoli Duan, Xiaoyun Qian, Xia Gao   +8 more
wiley   +1 more source

Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer.

Journal of Clinical Oncology, 2016
PURPOSE Cisplatin is widely used but highly ototoxic. Effects of cumulative cisplatin dose on hearing loss have not been comprehensively evaluated in survivors of adult-onset cancer.
R. Frisina, H. Wheeler, S. Fosså, S. Kerns, C. Fung, H. Sesso, P. Monahan, D. Feldman, R. Hamilton, D. Vaughn, C. Beard, A. Budnick, Eileen M Johnson, Shirin Ardeshir-Rouhani-Fard, L. Einhorn, S. Lipshultz, M. Dolan, L. Travis   +17 more
semanticscholar   +1 more source

Questions of diagnosing and treating Meniere's disease [PDF]

The possibilities of diagnosis and treatment of Meniere's disease are considered. Attention is given to the use of dehydration tests which are based on glycerol administration or intravenous injection of furosemide.
Khechinashvili, S. N.
core   +1 more source