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Total Artificial Hearts [PDF]

open access: possible, 1990
The first attempt to utilize a total artificial heart (TAH) was by Demikhov (Figure 33.1), who removed a dog’s heart and replaced it with a mechanical device1. His original plan was to maintain an artificial circulation, so that the organs from a cadaver could be used for transplantation1.
E. Solis, MUNERETTO, Claudio, C. Cabrol
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The Artificial Heart

New England Journal of Medicine, 2004
The story of the first implantation of a permanent artificial heart and the blizzard of reaction.
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The Artificial Heart [PDF]

open access: possible, 1984
Each year almost one million people in this country die from heart disease, and more than 500,000 from coronary artery insufficiency.1,2 The development of techniques to revascularize coronary arteries while helping many has not yet significantly decreased this mortality rate.
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The total artificial heart

Nature Medicine, 2003
Over the past 50 years, significant advances have been made in the development of total artificial hearts (TAH). These advances have most recently led to a clinical trial of a unique, transcutaneously powered TAH.
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Physiology of the Artificial Heart

Biomaterials, Medical Devices, and Artificial Organs, 1975
Numerous deviations from normal physiology formerly ascribed to artificial heart pumping actually resulted from experimental artifacts. Recent results indicate that infection, thromboembolism, pulmonary pathology, and renal deterioration could be considered mostly nonspecific artifacts of mechanical heart implantation.
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Control of the Artificial Heart

ASAIO Journal, 1996
The artificial heart (AH) is devoid of physiologic connections to the recipient's native feedback control loops. Control of an AH can be either passive or dynamic. Passive intrinsic control provides limited AH response to physiologic demands. Dynamic control requires the sensing of metabolic and hemodynamic signals and their incorporation into self ...
Kevin D. Murray   +2 more
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The Artificial Heart

Archives of Surgery, 1977
A multidisciplinary group has designed, fabricated, and evaluated an artificial heart. The heart consists of two smooth-surfaced sac-type pumps, two pneumatic power units, and an electronic control system. The artificial heart has been employed in 22 calves.
John A. Waldhausen   +7 more
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The Total Artificial Heart

AACN Advanced Critical Care, 1991
In the early 1800s, an awareness of potential ventricular failure stimulated interest in artificial heart replacement. In 1937 the first total artificial heart (TAH) was implanted into the chest of a dog by Russian physicians. The primary driving force for mechanical cardiac assistance developed from the necessity for circulatory assistance in order to
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The Artificial Heart Juggernaut

The Hastings Center Report, 1989
The Artificial Heart Juggernaut In May 1985 a panel of experts urged the National Institutes of Health to resume funding to develop a totally implantable permanent artificial heart: Fully implantable ventricular assist systems, in which an auxiliary pump takes over the function of the diseased ventricle, may be beneficial for some patients; for other ...
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Artificial hearts. Permanent and temporary

Health Policy, 1986
A little more than three years ago, at the University of Utah in Salt Lake City, Dr. William DeVries implanted a Jarvik-7 artificial heart in a 61-year-old patient named Barney Clark. The patient lived 112 days with the device before succumbing to renal failure, infection, and pseudomembranous colitis.1 His stormy clinical course had been marked by ...
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