Results 31 to 40 of about 777,469 (303)

Control system for an artificial heart [PDF]

, 1970
Inexpensive industrial pneumatic components are combined to produce control system to drive sac-type heart-assistance blood pump with controlled pulsatile pressure that makes pump rate of flow sensitive to venous /atrial/ pressure, while stroke is ...
Gebben, V. D., Webb, J. A., Jr.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Eliminating artificial trans fatty acids in Argentina: estimated effects on the burden of coronary heart disease and costs [PDF]

, 2015
Objective: To estimate the impact of Argentine policies to reduce trans fatty acids (TFA) on coronary heart disease (CHD), disability-adjusted life years (DALYs) and associated health-care costs.
Augustovski, Federico Ariel, Caporale, Joaquin, Elorriaga, Natalia, Garay, Ulises, Matta, Maria Gabriela, Mozaffarian, Dariush, Pichón-Riviere, Andrés, Poggio, Rosana, Rubinstein, Adolfo Luis   +8 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Thermally induced magnetic relaxation in square artificial spin ice

, 2016
The properties of natural and artificial assemblies of interacting elements, ranging from Quarks to Galaxies, are at the heart of Physics. The collective response and dynamics of such assemblies are dictated by the intrinsic dynamical properties of the ...
Andersson, M. S., Hjörvarsson., B., Kapaklis, V., Mathieu, R., Nordblad, P., Pappas, S. D., Stein, A., Stopfel, H., Östman, E.   +8 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Aortic valve imaging using 18F-sodium fluoride: impact of triple motion correction

EJNMMI Physics, 2022
Background Current 18F-NaF assessments of aortic valve microcalcification using 18F-NaF PET/CT are based on evaluations of end-diastolic or cardiac motion-corrected (ECG-MC) images, which are affected by both patient and respiratory motion.
Martin Lyngby Lassen, Evangelos Tzolos, Daniele Massera, Sebastien Cadet, Rong Bing, Jacek Kwiecinski, Damini Dey, Daniel S. Berman, Marc R. Dweck, David E. Newby, Piotr J. Slomka   +10 more
doaj   +1 more source

Ancient harbour infrastructure in the Levant: tracking the birth and rise of new forms of anthropogenic pressure

, 2014
Beirut, Sidon and Tyre were major centres of maritime trade from the Bronze Age onwards. This economic prosperity generated increased pressures on the local environment, through urbanization and harbour development.
Carayon, N., Kaniewski, D., Marriner, N., Morhange, C.   +3 more
core   +4 more sources

Role of Artificial Intelligence (AI) art in care of ageing society: focus on dementia [PDF]

, 2019
open access articleBackground: Art enhances both physical and mental health wellbeing. The health benefits include reduction in blood pressure, heart rate, pain perception and briefer inpatient stays, as well as improvement of communication skills and ...
Harwood, Tracy, Maltby, John, Mukaetova-Ladinska, Elizabeta   +2 more
core   +1 more source