Results 181 to 190 of about 319,815 (308)

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Clinical role of echocardiography in LVAD outflow graft abnormalities: redefining the diagnostic paradigm. [PDF]

Eur Heart J Imaging Methods Pract
Nuzzi V, Cipriani M, Carluccio E, Fortuni F.   +3 more
europepmc   +1 more source

Using Lacunarity to Characterize Pore Distribution in Scaffolds

, 2011
Deriu, Marco Agostino, Falvo D'Urso Labate, Giuseppe Vittorio Ugo, Massai, Diana Nada Caterina, Montevecchi, Franco Maria, Morbiducci, Umberto, Pennella, Francesco, Schiavi, Alessandro   +6 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Temporary Left Ventricular Assist Device for Peripartum Cardiogenic Shock as a Bridge to Cesarean Delivery. [PDF]

JACC Case Rep
Van Oosbree A, Samson M, Gore A, Nielsen C, Atkins JL, Heinke T, Chang E, Goodier C, McElwee E, Rao VN.   +9 more
europepmc   +1 more source

Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia

Advanced Healthcare Materials, EarlyView.
This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder   +5 more
wiley   +1 more source

Are We Missing the Obvious? Lessons From Aortic Root Thrombosis After LVAD Implantation. [PDF]

JACC Case Rep
Divya A, Dalal N.
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Single-Center Experience with the HeartMate 3 Assist Device in Pediatric Patients with Cardiomyopathy. [PDF]

Medicina (Kaunas)
Hulman M, Artemiou P, Stuschkova D, Durdik S, Nosal M, Hrubsova Z, Kovacikova L, Kunovsky P, Zahorec M, Kovac M, Gasparovic I.   +10 more
europepmc   +1 more source

Reversing Heart Failure With a Ventricular Anchoring Device: Another Hope for Myopathic Mitral Regurgitation. [PDF]

, 2020
Rame, J. Eduardo
core   +1 more source