Results 261 to 270 of about 261,118 (334)

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Editorial: Physio-logging in humans: recent advances and limitations in wearable devices for biomedical applications. [PDF]

Front Physiol
Landry C, Yavarimanesh M, Drummond CK.
europepmc   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

How AI is used in FDA-authorized medical devices: a taxonomy across 1,016 authorizations. [PDF]

NPJ Digit Med
Singh R, Bapna M, Diab AR, Ruiz ES, Lotter W.   +4 more
europepmc   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Left Ventricular Mechanical Circulatory Support Devices for Cardiogenic Shock After Myocardial Infarction. [PDF]

Cardiol Ther
Giao DM, Giugliano RP.
europepmc   +1 more source

Practical Guide to the Design of Granular Hydrogels for Customizing Complex Cellular Microenvironments

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley   +1 more source

Multicentre comparison of various microaxial pump devices as a bridge to durable assist device implantation. [PDF]

ESC Heart Fail
Medina ML, Lewin D, Treede H, Rojas SV, Bernhardt A, Billion M, Meyer AL, Netuka I, Kooij J, Pieri M, Loforte A, Rinaldi M, Szymanski MK, Kraajieveld AO, Moeller CJH, Akhyari P, Jawad K, Schmack B, Färber G, Haneya A, Zimpfer D, Nersesian G, Djordjevic I, Saeed D, Gustafsson F, Scandroglio AM, Meyns B, Hofmann S, Belohlavek J, Gummert J, Lanmueller P, Potapov EV, Oezkur M.   +32 more
europepmc   +1 more source

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

Bridging to orthotopic heart transplant: Reducing the risk of intra-operative blood loss. [PDF]

JHLT Open
Miller P, Akcelik A, Murillo A, Baskin A, Merriman A, Arammash M, Kiran S, Smith J, Fiedler AG.   +8 more
europepmc   +1 more source