Results 11 to 20 of about 338,458 (292)

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Transduction of primary human natural killer (NK) cells with lentiviral vectors has historically been challenging. We sought to evaluate multiple parameters to optimize lentiviral transduction of human peripheral blood NK cells being expanded to large ...
David S.J. Allan   +6 more
doaj   +1 more source

Medium term results following heart transplantation for end stage heart failure: A single center experience of 257 patients

open access: yesIndian Heart Journal, 2020
Objective: End stage heart failure is a lethal disease with a dismal 5 year survival. Heart transplantation has proven to be a highly effective modality of treatment in appropriately selected group of such patients.
K.R. Balakrishnan   +9 more
doaj   +1 more source

Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic Dissection

open access: yesFrontiers in Cardiovascular Medicine, 2021
Filamins (FLNs) are actin cross-linking proteins, and as scaffolding proteins, FLNs are closely associated with the stabilization of the cytoskeleton. Nevertheless, the biological importance of FLNs in aortic dissection (AD) has not been well-elucidated.
Yue Chen   +18 more
doaj   +1 more source

Long-term outcomes after chest wall resection and repair with titanium bars and sternal plates

open access: yesFrontiers in Surgery, 2022
ObjectivesEn-bloc complete resection remains the treatment of choice for localized chest wall (CW) tumors. Titanium bars reconstruction demonstrated encouraging results with satisfactory early outcomes.
Hugo Clermidy   +11 more
doaj   +1 more source

Risks and Epidemiology of Infections After Lung or Heart–Lung Transplantation [PDF]

open access: goldTransplant InfectionsFourth Edition, 2016
Len O, Roman A, Gavaldà J.
europepmc   +2 more sources

Expanded NK cells used for adoptive cell therapy maintain diverse clonality and contain long-lived memory-like NK cell populations

open access: yesMolecular Therapy: Oncolytics, 2023
Multiple clinical trials exploring the potential of adoptive natural killer (NK) cell therapy for cancer have employed ex vivo expansion using feeder cells to obtain large numbers of NK cells.
David S.J. Allan   +7 more
doaj   +1 more source

Heart transplantation in a patient with complex heart lung disease: a case report

open access: yesKorean Journal of Transplantation, 2021
Heart disease is often accompanied by lung disease as they share the same risk factors. Heart or lung transplantation is regarded as a definitive treatment for the end-stage disease of each, while the expected median survival for lung transplantation is ...
Seok Hyun Kim   +3 more
doaj   +1 more source

Totally endoscopic non-robotic excision of aortic valve fibroelastoma: a case report

open access: yesJournal of Cardiothoracic Surgery, 2022
Background Papillary fibroelastomas (PFEs) are a rare subtype of benign primary cardiac tumours, which are most commonly found on the aortic valve. Although median sternotomy is still used frequently there has been different attempts to remove the aortic
Sadia Batool   +3 more
doaj   +1 more source

Integrating Bulk Transcriptome and Single-Cell RNA Sequencing Data Reveals the Landscape of the Immune Microenvironment in Thoracic Aortic Aneurysms

open access: yesFrontiers in Cardiovascular Medicine, 2022
Thoracic aortic aneurysm (TAA) is a life-threatening cardiovascular disease whose formation is reported to be associated with massive vascular inflammatory responses.
Qunhui Wang   +12 more
doaj   +1 more source

BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection

open access: yesPharmacological Research, 2022
Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the excessive lipid peroxidation accumulation.
Yue Chen   +11 more
doaj   +1 more source

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