Results 251 to 260 of about 185,979 (321)

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β [PDF]

, 2018
et al,, Gelman, Andrew E, Hsiao, Hsi-Min, Kreisel, Daniel, Lavine, Kory J, Li, Wenjun, Liu, Yongjian, Luehmann, Hannah P, Puri, Varun, Ruiz-Perez, Daniel, Scozzi, Davide, Spahn, Jessica H, Takahashi, Tsuyoshi, Tanaka, Satona, Turam, Cem   +14 more
core   +1 more source

Age‐related penetrance of phospholamban p.Arg14del cardiomyopathy

European Journal of Heart Failure, EarlyView.
Age‐related penetrance of phospholamban (PLN) p.Arg14del cardiomyopathy. ECG, electrocardiogram; ICD, implantable cardioverter‐defibrillator; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging; PVC, premature ventricular contraction; SCD, sudden cardiac death; VF, ventricular fibrillation; VT,
Tom E. Verstraelen, Freyja H.M. van Lint, Remco de Brouwer, Virginnio M. Proost, Esmee van Drie, Laurens P. Bosman, Lotte Weverink, Karim Taha, Thais Bueren, Aeilko H. Zwinderman, Cathelijne Dickhoff, Toon Oomen, Bas A. Schoonderwoerd, Tjeerd Germans, Arjan C. Houweling, Juan R. Gimeno‐Blanes, Folkert W. Asselbergs, Paul A. van der Zwaag, Anneline S.J.M. te Riele, Rudolf A. de Boer, Maarten P. van den Berg, J. Peter van Tintelen, Arthur A.M. Wilde   +22 more
wiley   +1 more source

Heart-lung transplantation for end-stage respiratory disease in cystic fibrosis patients.

, 1993
James G. Scott, C. Dennis, P. Mullins
openalex   +1 more source

Exercise haemodynamics in pulmonary hypertension – a prospective pressure–volume loop study on right ventricular adaptation and prognosis

European Journal of Heart Failure, EarlyView.
Multimodal assessment during exercise distinguishes clinically relevant right ventricular (RV) adaptation patterns (homeometric and heterometric adaptation) in pulmonary hypertension. Disease controls are patients with invasive exclusion of pulmonary hypertension.
Bruno R. Thal, Zvonimir A. Rako, Nils C. Kremer, Athiththan Yogeswaran, Patrick Janetzko, Selin Yildiz, Stephan Rosenkranz, Hossein Ardeschir Ghofrani, Werner Seeger, Friedrich Grimminger, Khodr Tello   +10 more
wiley   +1 more source

Finerenone according to insulin resistance in heart failure: Insights from the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
Insulin resistance in heart failure with mildly reduced or preserved ejection fraction: insights from FINEARTS‐HF. CI, confidence interval; CV, cardiovascular; eGDR, estimated glucose disposal rate; HF, heart failure. Aims The estimated glucose disposal rate (eGDR) is a simple, non‐invasive measure of insulin resistance. In this exploratory analysis of
John W. Ostrominski, Brian L. Claggett, Akshay S. Desai, Pardeep S. Jhund, Carolyn S.P. Lam, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Katja Rohwedder, Meike Brinker, Patrick Schloemer, John J.V. McMurray, Scott D. Solomon, Muthiah Vaduganathan   +15 more
wiley   +1 more source

Impact of age, sex, therapeutic intent, race and severity of advanced heart failure on short-term principal outcomes in the MOMENTUM 3 trial [PDF]

, 2018
et al,, Itoh, Akinobu
core   +1 more source

A Mucoadhesive Hydrogel for Precise Resveratrol Delivery in the Management of Inflammatory Bowel Disease

Food Frontiers, EarlyView.
CMTR‐Gel targeting to the inflamed mucosa by electrostatic interactions. ABSTRACT Natural drug‐food homology compounds have vast therapeutic potential, particularly for inflammatory bowel disease (IBD), but their poor water solubility, instability, and limited mucosal availability hinder their clinical translation.
Wenqiu Xu, Xiaojia Lv, Jilun Ye, Ying Li, Hua Yu, Chenyang Li, Haiqiang Wu, Wei Xiong   +7 more
wiley   +1 more source

Hesperetin Mitigate Idiopathic Pulmonary Fibrosis by Regulating Gut Microbiota and Acetate and Butyrate Levels via the Gut‐Lung Axis

Food Frontiers, EarlyView.
Hesperetin inhibits bleomycin‐induced idiopathic pulmonary fibrosis by regulating gut microbiota and acetate and butyrate levels via the gut‐lung axis. ABSTRACT In the post‐epidemic and aging era, idiopathic pulmonary fibrosis (IPF) has become one of the major diseases endangering human health.
Xia Meng, Zeren Cheng, Xianpu Huang, Mengqi Fu, Ling Shen, Kejing Tang, Shuxun Liu, Mingfei Yao, Qing Gu, Ping Li   +9 more
wiley   +1 more source