Results 261 to 270 of about 185,979 (321)

PHENOMENON OF DEMIKHOV. "TRANSPLANTATION OF VITAL ORGANS IN EXPERIMENT" (1960). HOMOPLASTIC ORGAN TRANSPLANTATION: OF AN ISOLATED HEART, ISOLATED LUNG, KIDNEY, HEAD, HALF OF THE TRUNK, AND THE WHOLE TRUNK

, 2017
S. P. Glyantsev
openalex   +2 more sources

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Anti‐CD47 antibody‐decorated and cisplatin‐containing mesoporous silica nanoparticles for targeted chemoimmunotherapy of colorectal cancer in a patient‐derived organoids xenograft model

Interdisciplinary Medicine, EarlyView.
Upon targeted binding to CD47‐overexpressing colorectal cancer (CRC) cells, the nanoparticles disrupt signal regulatory protein α‐CD47 signaling and allow for the restoration of innate immune response by tumor‐associated macrophages (TAMs) against CRC.
Albert Yu, Yibo Hou, Kaibin Huang, Xucan Gao, Rong Zeng, Chaowei Zhu, Chunhui Sun, Guocai Wang, Lei Ye, Shaohua Ma, Tian Meng, Bing Guo, Yubo Zhang, Xiaoyong Dai   +13 more
wiley   +1 more source

Model Informed Precision Dosing of Tacrolimus in Children Following Heart Transplant

The Journal of Clinical Pharmacology, EarlyView.
Abstract Tacrolimus is a first‐line immunosuppressant used after solid organ transplantation that suffers from extensive intra‐ and inter‐patient variability and a narrow therapeutic window. Its critical role in a fragile population, coupled with the difficulties identifying and maintaining an appropriate dose within a given patient, make it an ideal ...
Jadon S. Wagstaff, Shaun S. Kumar, Kimberly M. Molina, Joseph E. Rower   +3 more
wiley   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

Comparative diagnostic accuracy study of point of care ultrasound techniques for detection of left atrial enlargement by hospital medicine physicians from archived echocardiogram images

Journal of Hospital Medicine, EarlyView.
Abstract Background Left atrial enlargement (LAE) is predictive of cardiovascular morbidity and mortality. Prior studies of point‐of‐care ultrasound (POCUS) interpretation methods for identifying LAE utilized older echocardiographic reference ranges. Objectives Compare the test characteristics of hospitalist‐performed POCUS techniques for identifying ...
Christopher J. Smith, Jesse Umbra, Sofia Quintero, Austin Wilson, Elizabeth Lyden, Nidish Tiwari, Brian Shahan, Jana Wardian   +7 more
wiley   +1 more source

Motion Mitigation Techniques for Abdominal and Cardiac MR Imaging

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT MRI of the heart and abdominal organs provides unparalleled soft tissue contrast and quantitative biomarkers, yet remains highly susceptible to physiological motion. Contractions of the myocardium, respiratory excursions, peristalsis, vascular pulsatility, and unpredictable bulk patient movement generate artifacts that impair image quality ...
Eric M. Schrauben, Gastao Lima da Cruz, Christopher W. Roy, Thomas Küstner   +3 more
wiley   +1 more source