Results 71 to 80 of about 4,078,345 (257)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Position paper on physical activity for children and young people
, 2001 The National Heart Alliance is an independent non-governmental organisation which aims to increase co-operation among organisations involved in the fight against heart disease. ➢ The National Heart Alliance includes representation from a wide range of
National Heart Alliance
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Sacred Heart University Magazine, Winter 2001 [PDF]
, 2001 Special issue: Journal of Giving. The Sacred Heart University Journal of Giving is a register of donors to the University for fiscal year July 1, 1999 to June 30 ...
Sacred Heart University,
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Physiological Biomimetic Culture System for Pig and Human Heart Slices [PDF]
, 2019 RATIONALE: Preclinical testing of cardiotoxicity and efficacy of novel heart failure therapies faces a major limitation: the lack of an in situ culture system that emulates the complexity of human heart tissue and maintains viability and functionality ...
Abouleisa, Riham +19 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Happy Heart national survey: a report on health behaviour in Ireland.
, 1994 The Happy Heart Community Programme was established in 1990, building on the experiences of the Kilkenny Health Project and of the first Happy Heart Project in Malahide.
Irish Heart Foundation
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Cells, 2019 Since their discovery 20 years ago, microRNAs have been related to posttranscriptional regulation of gene expression in major cardiac physiological and pathological processes.
Robin M.W. Colpaert, Martina Calore
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
, 2015 New data mapped by the Heart Foundation reveals the rates of heart attack and cardiac arrest for each local government area in Victoria, and for some communities the picture looks bleak. The latest Victorian Heart Maps, show a graphic picture of ...
National Heart Foundation of Australia
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