Results 141 to 150 of about 1,551,822 (283)

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy

open access: yesJournal of Anatomy, EarlyView.
We provide a description of human embryonic cerebral arterial development based on whole‐mount immunostaining, tissue clearing, three‐dimensional (3D) light‐sheet microscopy imaging, and anatomically informed virtual segmentation of human embryos. Findings are compared with adult radiological anatomy. We provide a detailed account of the development of
Eimad Shotar   +30 more
wiley   +1 more source

Perceptions and experiences of entrustable professional activities implementation in postgraduate medical education: A qualitative evidence synthesis

open access: yesMedical Education, EarlyView.
Abstract Background Entrustable professional activities (EPAs) define essential professional tasks and responsibilities that can inform curriculum, teaching, supervision, developmental progression and assessment. Despite widespread implementation in postgraduate medical education, experiences and perceptions of EPAs remain fragmented, raising questions
Justin Phung   +6 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

Clinical Significance of Organ Preservation Fluid Cultures in Pediatric Abdominal Solid Organ Transplantation

open access: yesTransplant Infectious Disease, EarlyView.
In this pediatric abdominal solid organ transplant cohort, preservation fluid‐related infections were rare but occurred in infant liver transplant recipients whose preservation fluid cultures grew pathogenic organisms. These findings suggest that routine bacterial preservation fluid cultures may be most useful for identifying clinically significant ...
Hassan A. Jamal   +5 more
wiley   +1 more source

Utilization patterns of low‐titer group O whole blood in a level 1 trauma center

open access: yesTransfusion, EarlyView.
Abstract Background Whole blood (WB) is an easy‐to‐use resuscitation fluid. As more low‐titer group O WB has become available at our hospital, it is being used in an increasingly diverse range of situations, both pre‐hospital and in‐hospital. Study Design and Methods We conducted a retrospective analysis of all WB units issued by our transfusion ...
Maryam Asif   +5 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Aortopathy: limitations of diameter-based decision-making: a case report. [PDF]

open access: yesEur Heart J Case Rep
Senftinger J   +4 more
europepmc   +1 more source

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