Sinus of Valsalva aneurysm is a rare defect that can present with fatal complications in case of rupture. Heart failure symptoms are common due to high fraction of the resultant shunt.
Kameel Kassab MD +5 more
doaj +1 more source
Biventricular aneurysm in a dog
: An aneurysm is defined as a localized dilation of a blood vessel or heart. It may have either a congenital or an acquired origin and occurs in both humans and animals.
Karim Cristhine Pase Montagnini +5 more
doaj +1 more source
Platypnea-orthodeoxia due to osteoporosis and severe kyphosis: a rare cause for dyspnea and hypoxemia [PDF]
Platypnea orthodeoxia is a rare disorder characterized by dyspnea and arterial desaturation, exacerbated by the upright position and relieved when the subject is recumbent.
Teupe, Claudius HJ +6 more
core +1 more source
Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou +4 more
wiley +1 more source
Submitral Aneurysm in a Patient with a Normal Electrocardiogram
A ventricular aneurysm entails well-known risks for the patient such as heart failure, potentially lethal arrhythmias, and systemic embolic phenomena.
Carlos A. Solis-Olivares +2 more
doaj +1 more source
The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. [PDF]
Introduction Chronic thoracic aortic aneurysm (CTAA) affecting the arch or descending aorta is an indolent but life-threatening condition with a rising prevalence as the UK population ages.
Catarino, P. +42 more
core +1 more source
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Numerical Study of the Effects of Aneurysm and Stenosis in the Left Coronary Artery on the Human Blood Stream [PDF]
The heart is the most important muscular organ in human's body, which pumps blood through the arteries to supply the body with oxygen and nutrients. The heart is supplied by the coronary blood vessel; therefore, the effect of aneurysm and stenosis in ...
N Mahmoud, A AI.allaq
doaj +1 more source
A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu +17 more
wiley +1 more source

