Results 121 to 130 of about 2,128,557 (346)

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Modelling Effect of Heart Failure on the Electrical Activity of Sheep Atria

Computing in Cardiology Conference (CinC), 2018
Heart failure (HF) is associated with cardiac arrhythmias, which impairs cardiac electromechanics that causes dysfunction of cardiac muscle contraction leading to increased risks of morbidity and mortality. Previous studies have revealed that HF causes alteration to the electrophysiological and structural properties of the atria.
Henggui Zhang, Nouf R Alshwaira
openaire   +2 more sources

Higher frequencies of BCRP+ cardiac resident cells in ischaemic human myocardium [PDF]

, 2017
Aims Several cardiac resident progenitor cell types have been reported for the adult mammalian heart. Here we characterize their frequencies and distribution pattern in non-ischaemic human myocardial tissue and after ischaemic events. Methods and results
Emmert, Lorenz S., Emmert, Maximilian Y., Gawol, Anke, Gruh, Ina, Haverich, Axel, Ismail, Issam, Martens, Andreas, Martin, Ulrich, Schmidt-Richter, Ingrid, Seifert, Burkhardt   +9 more
core  

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Knowledge, Attitude, and Practice on Atrial Fibrillation and Atrial Fibrillation Screening in High‐Risk Population: A Cross‐Sectional Study

AGING MEDICINE, EarlyView.
Distribution of KAP scores for participants ≤ 65 versus > 65 years. ABSTRACT Objectives Atrial fibrillation (AF) is a common clinical arrhythmia. Failure to identify AF leaves patients at a considerably higher risk of disability and death, making its early screening and prevention extremely important. This study aimed to investigate knowledge, attitude,
Zhong Yi, Xinxin Yan, Shaozhi Xi, Lijuan Zhu, Rui Liu, Jing Li, Songwei Ru, Xiu Zheng, Jingxuan Qiu, Chunqi Wang, Na Guo, Yimin Wang, Dayong Gao   +12 more
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Parametric Design of Continuum Robots Using Interlocking Ball Joints

Advanced Intelligent Systems, EarlyView.
Herein, a parametric design methodology is introduced for producing a wide variety of modular ball joint‐based continuum robots. It is demonstrate by designing a magnetically actuated continuum robot for cardiac ablations. The methodology is released as an open‐source computer‐assisted design extension that automatically designs continuum robots based ...
Alexandre Mesot, Quentin Boehler, Florian Heemeyer, Sean Lyttle, Buse Aktaş, Bradley J. Nelson   +5 more
wiley   +1 more source

Role of Fiber Orientation in Atrial Arrythmogenesis [PDF]

, 2014
Electrical wave-front propagation in the atria is determined largely by local fiber orientation. Recent study suggests that atrial fibrillation (AF) progresses with enhanced anisotropy.
Belvin, Thomas, Castro, Simon, Colman, Michael, Jarvis, Jonathan, Kharche, Sanjay, Smaill, Bruce, Stephenson, Robert, Zhang, Henggui, Zhao, Jichao   +8 more
core   +1 more source

Characterizing the Healthcare Utilization and Costs of Hereditary Hemorrhagic Telangiectasia

American Journal of Hematology, EarlyView.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is the second‐most common inherited bleeding disorder worldwide, afflicting one in 4000–5000 people, and is the most morbid inherited bleeding disorder of women. HHT causes recurrent severe epistaxis, chronic gastrointestinal bleeding, heavy menstrual bleeding, and arteriovenous malformations in the ...
Hanny Al‐Samkari, Tracy J. Mayne, Misty Troutt, Hemant Patle, Marianne Clancy, Eric Duhaime   +5 more
wiley   +1 more source

Multipolar Left Ventricular Lead Implantation in a Unique Coronary Sinus: Direct Drainage of the Posterior Vein into the Right Atrium

Journal of Tehran University Heart Center, 2018
The coronary sinus, whose electrical features play an important role in cardiac arrhythmias, is the integral part of the cardiac venous system. Here we describe a 67-year-old male patient with congestive heart failure who was referred to our hospital ...
Ahmet Taha Alper, Mert İlker Hayıroğlu, Hakan Barutça, Ahmet İlker Tekkeşin, Ceyhan Türkkan   +4 more
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