Results 201 to 210 of about 76,780 (342)

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC‐Derived Cardiac Myocytes

open access: yesCytoskeleton, EarlyView.
ABSTRACT Sarcomeres are the fundamental contractile units of striated muscle. The functional roles of the cardiac‐specific myosin heavy chains, MYH6 (α myosin II) and MYH7 (β myosin II) during sarcomere assembly remain controversial. To address this, we utilized a selective MYH7 inhibitor, mavacamten, in combination with siRNA‐mediated knockdown of ...
James B. Hayes, Dylan T. Burnette
wiley   +1 more source

Association Between Pre-Admission ATRIA Scores and Initial Stroke Severity in Acute Ischemic Stroke: A Cross-Sectional Study. [PDF]

open access: yesJ Clin Med
Süygün H   +9 more
europepmc   +1 more source

Micellar Liquid Chromatography Determination of Edoxaban in Oral Solid Dosage Forms: Theoretical Aspects and Validation

open access: yesChemMedChem, EarlyView.
A method is developed and validated to quantify edoxaban in solid oral dosage forms using micellar liquid chromatography. A chemometric strategy is used to study the retention mechanism. The procedure is green, economic, safe, and easy to handle; offers high sample throughput; and is reliable, thus useful for pharmaceutical quality control.
Juan Peris‐Vicente   +4 more
wiley   +1 more source

Do hypoxemia or hypercapnia predispose to atrial fibrillation in breathing disorders, and, if so, how? [PDF]

open access: yes, 2010
Andrew C. Rankin   +13 more
core   +1 more source

Increased plasma concentration of atrial natriuretic factor with squamous cell carcinoma invasion of the right and left atria of the heart [PDF]

open access: bronze, 1989
Dan S. Bradford   +4 more
openalex   +1 more source

Risk of Infections with SGLT2 Inhibitors Versus DPP4 Inhibitors: A Population‐Based Cohort Study Using Antibiotic Dispensing Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study compared the number and cumulative dose of antibiotic dispensings among new users of sodium–glucose cotransporter‐2 (SGLT2) inhibitors and dipeptidyl peptidase‐4 (DPP4) inhibitors following hospital discharge in individuals with type 2 diabetes.
Maria J. Alfonso Arvez   +5 more
wiley   +1 more source

Effectiveness and Safety of Reduced‐Dose Prasugrel in an East Asian Population: PRASFIT‐ACS Emulation Using National Health Insurance Claims Data

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Li‐Wen Huang   +6 more
wiley   +1 more source

Atrial electrical alterations with intact cardiac structure and contractile function in a mouse model of an HCM-linked <i>ACTN2</i> variant. [PDF]

open access: yesJ Mol Cell Cardiol Plus
Noureddine M   +9 more
europepmc   +1 more source

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