Results 211 to 220 of about 2,119,388 (341)

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC‐Derived Cardiac Myocytes

Cytoskeleton, EarlyView.
ABSTRACT Sarcomeres are the fundamental contractile units of striated muscle. The functional roles of the cardiac‐specific myosin heavy chains, MYH6 (α myosin II) and MYH7 (β myosin II) during sarcomere assembly remain controversial. To address this, we utilized a selective MYH7 inhibitor, mavacamten, in combination with siRNA‐mediated knockdown of ...
James B. Hayes, Dylan T. Burnette
wiley   +1 more source

Baseline and stimulated ANF plasma levels [PDF]

, 1987
Arendt, Rainer M., Erdmann, E., Gerbes, Alexander L., Glatthor, C., Kemkes, B., Kramer, Herbert J., Riedel, Angelika, Ritter, D., Schimak, M., Stangl, E., Zähringer, J.   +10 more
core   +1 more source

Cardioneuroablation for Drug Refractory Vasovagal Syncope After COVID-19 Infection

JACC: Case Reports
Cardioneuroablation is a novel approach to treat patients with recurrent vasovagal syncope (VVS), targeting the ganglionated plexi around the atria and thus reducing the vagal input to the heart.
Stefanos Zafeiropoulos, MD, PhD, Nicholas J. Beccarino, MD, Stavros Stavrakis, MD, PhD, Stavros Zanos, MD, PhD, Raman Mitra, MD, PhD   +4 more
doaj  

Differential Pattern of Endothelin-1-Induced Inotropic Effects in Right Atria and Left Ventricles of the Human Heart

, 2000
Stefan Dhein, C Giessler, Thekla Wangemann, RE Silber, H.-R. Zerkowski, Otto‐Erich Brodde   +5 more
openalex   +1 more source

Further Structure‐Activity Relationship of G Protein‐Gated Inwardly Rectifying Potassium Channels 1/2 Activators: Synthesis and Biological Characterization of In Vitro Tool Compounds

ChemMedChem, EarlyView.
Work presented here details the design and characterize novel G protein‐gated inwardly rectifying potassium channels (GIRK)1/2 activators. A new 4,4‐difluorocyclohexylpyrazole have been identified that confers improved potency and selectivity for GIRK1/2 versus GIRK1/4.
Sumaiya Nahid, Fahad Imtiaz Rahman, Yu Du, Brittany D. Spitznagel, Sandeep K. Singh, Yashpal S. Chhonker, Daryl J. Murry, C. David Weaver, Corey R. Hopkins   +8 more
wiley   +1 more source

Subtle Symptoms of Large Biatrial Myxomas: A Case Study and Surgical Insights. [PDF]

Am J Case Rep
Naeem A, Emeasoba EU, Khan MH, Shani J, Sadiq A, Azar O, Ribakove GH, Saunders PC.   +7 more
europepmc   +1 more source

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

Clinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang, Logan Brooks, Denise M. Boudreau, Pascal Chanu, Amita Joshi, Bianca Vora, Rui Zhu   +6 more
wiley   +1 more source

Surgical resection of a rare biatrial giant sarcoma: a case report. [PDF]

J Cardiothorac Surg
Wu J, Lin Y, Liu J, Wu J, Zhang H, Liang C.   +5 more
europepmc   +1 more source

The cardiac atria are chambers of active remodeling and dynamic collagen turnover during evolving heart failure

, 2004
Anjum Khan, Gordon W. Moe, Nafiseh Nili, Effat Rezaei, Muhammad Eskandarian, Jagdish Butany, Bradley H. Strauss   +6 more
openalex   +1 more source

Myofiber Architecture of the Human Atria as Revealed by Submillimeter Diffusion Tensor Imaging

Circulation: Arrhythmia and Electrophysiology, 2016
Farhad Pashakhanloo, D. Herzka, H. Ashikaga, S. Mori, N. Gai, D. Bluemke, N. Trayanova, E. McVeigh   +7 more
semanticscholar   +1 more source