Results 311 to 320 of about 5,502,248 (393)

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

open access: yesAdvanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung   +6 more
wiley   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

open access: yesAdvanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño   +5 more
wiley   +1 more source

Quasi‐Periodic Surface Functionalization by Ultra‐Short Pulsed Laser Processing: Unlocking Superior Heat Transfer in Vapor Chambers

open access: yesAdvanced Functional Materials, EarlyView.
Ultra‐short pulsed laser processing (ULSP) enables scalable, open‐air fabrication of self‐organized, quasi‐periodic micro/nanostructures on copper using 100 µm laser beams, orders of magnitude larger than the resulting surface features. Integrated into ultra‐thin, wick‐free vapor chambers, these laser‐functionalized surfaces dramatically enhance ...
Anish Pal   +7 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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