Results 111 to 120 of about 159,275 (311)

The early stages of heart development: insights from chicken embryos [PDF]

open access: yes, 2016
The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan   +19 more
core   +2 more sources

Antimicrobial Behavior of Simvastatin‐Loaded Solution Blow‐Spun PLA/PEO/HA Scaffolds

open access: yesJournal of Applied Polymer Science, EarlyView.
Schematic for fiber spinning. ABSTRACT The development of three‐dimensional scaffolds with suitable biological properties is of crucial importance in bone repair. Incorporating antimicrobial functionality into these scaffolds can further enhance their clinical efficacy by helping prevent infections, particularly in patients undergoing orthopedic ...
João P. A. Caribé   +17 more
wiley   +1 more source

Trends in U.S. National Institutes of Health Funding for CHARGE Syndrome Research, 2000 to 2024

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Muhammad Othman   +2 more
wiley   +1 more source

Development of Respiratory Sinus Arrhythmia in Young Infants With Autism Spectrum Disorder, Preterm Birth, and Typical Development

open access: yesAutism Research, EarlyView.
ABSTRACT Respiratory sinus arrhythmia (RSA) is a key index of parasympathetic function and environmental adaptability. Lower resting RSA has been linked to preterm (PT) birth in infancy and autism spectrum disorder (ASD) in childhood, yet RSA across the first 2 years in young infants born PT or later diagnosed with ASD remains unknown.
Jessica Bradshaw   +3 more
wiley   +1 more source

Cytomegalovirus infection and congenital heart disease in children

open access: yesЖурнал инфектологии, 2019
Congenital heart defects account for about 30% of all anomaly of development in children. Cytomegalovirus infection suffered by a woman during pregnancy claims one of the leading places among teratogenic factors.Aim: to study clinical and pathogenetic ...
E. A. Каshuba   +6 more
doaj   +1 more source

Acute kidney injury and morbi‐mortality associated with “triple whammy” combination: Systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo   +4 more
wiley   +1 more source

Perventricular Device Closure of Native Congenital Muscular Ventricular Septal Defects in Small Infants   $\hspace{0.17em}$ ≤ 5 kg: Single‐Center Study of the Risk Factors for Failure of the Intervention and Non‐Optimal Outcome

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Perventricular device closure of muscular VSD in small infants is a less invasive option than surgical closure under cardiopulmonary bypass and offers better outcomes than palliative pulmonary artery banding. However, the specific risk factors that could affect procedural success and optimal outcomes have not been ...
Emine Hekim Yilmaz   +7 more
wiley   +1 more source

Honeycomb or Lotus Root‐Like Intracoronary Pattern: Insights From Optical Coherence Tomography of a Recanalized Thrombus

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Spontaneous recanalized coronary thrombus (SRCT) has been identified in autopsy studies as multiple interconnected channels separated by thin septa. Despite its potential clinical significance, SRCT remains underdiagnosed. Recent advances in intracoronary imaging, including optical coherence tomography (OCT), have elucidated its ...
Fernando Quevedo   +9 more
wiley   +1 more source

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

open access: yesESC Heart Failure
Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP)
Jules Hamers   +11 more
doaj   +1 more source

Prevalence and predictors of later feeding disorders in children who underwent neonatal cardiac surgery for congenital heart disease [PDF]

open access: yes, 2017
Aim We thought of assessing the prevalence and predictors of feeding disorders in patients with congenital heart defects after neonatal cardiac surgery.
Balmer, Christian   +5 more
core  

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