Results 111 to 120 of about 320,100 (253)

Congenital Heart Defects: CDC\u2019s Tracking and Research Activities

CDC works to better understand how often and why congenital heart defects (CHDs) occur, and the characteristics and health outcomes, use of services, and racial/ethnic differences of people living with CHDs. By learning more about those living with CHDs,

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Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

ESC Heart Failure
Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP)
Jules Hamers, Payel Sen, Sarala Raj Murthi, Laura Papanakli, Maria vonStumm, Francesca Baessato, Julie Cleuziou, Christian Meierhofer, Peter Ewert, Andreas Dendorfer, Daphne Merkus, Cordula M. Wolf   +11 more
doaj   +1 more source

Congenital heart defects in Kabuki syndrome

, 2013
Background: Kabuki syndrome (KS) is an entity of multiple congenital malformations withmental retardation with undetermined etiology. Congenital heart defects are one of the clinicalmanifestations of KS with insuffi cient elucidations.Methods: Literature
Yuan, Shi-Min; The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, Fujian Province, China
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5 Things To Know About Heart Defects

Heart defects are conditions that are present at birth and can affect the structure of a person\u2019s heart and the way it works. Heart defects are common, costly, and critical conditions that affect people throughout their lives.

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Amplatzer occluders – a breakthrough in the interventional treatment of congenital heart defects. 27 years of experience

This review synthesizes the experience of a single institution in the percutaneous closure of the most common congenital heart defects – atrial septal defect (ASD), ventricular septal defect (VSD), and patent ductus arteriosus (PDA) – using Amplatzer ...
Jacek Białkowski, Małgorzata Szkutnik
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Heterozygous loss-of-function variants of MEIS2 cause a triad of palatal defects, congenital heart defects, and intellectual disability

European Journal of Human Genetics, 2018
Rosalind Verheije, G. Kupchik, B. Isidor, H. Kroes, S. Lynch, L. Hawkes, M. Hempel, B. Gelb, J. Ghoumid, G. D'Amours, K. Chandler, C. Dubourg, S. Loddo, Z. Tümer, C. Shaw-Smith, M. Nizon, M. Shevell, Evelien Van Hoof, K. Anyane-Yeboa, G. Cerbone, J. Clayton-Smith, B. Cogné, P. Corre, A. Corveleyn, Marie de Borre, T. D. Hjortshøj, M. Fradin, M. Gewillig, E. Goldmuntz, G. Hens, E. Lemyre, H. Journel, U. Kini, F. Kortüm, C. Le Caignec, A. Novelli, S. Odent, F. Petit, Anya Revah-Politi, N. Stong, T. Strom, E. van Binsbergen, K. Devriendt, J. Breckpot   +43 more
semanticscholar   +1 more source

Juxtaposition of the atrial appendages in a patient with a simple ventricular septal defectCentral Message

JTCVS Techniques, 2021
Julie Cleuziou, MD, PhD, MBA, Jakob Kemmer, MD, Ursula Sauer, MD, Milka Pringsheim, MD   +3 more
doaj   +1 more source

Contribution of hypoxia-inducible factor 1alpha to pathogenesis of sarcomeric hypertrophic cardiomyopathy

Scientific Reports
Hypertrophic cardiomyopathy (HCM) caused by autosomal-dominant mutations in genes coding for structural sarcomeric proteins, is the most common inherited heart disease.
Sarala Raj Murthi, Andreas Petry, Bachuki Shashikadze, Jan B. Stöckl, Manuel Schmid, Gianluca Santamaria, Karin Klingel, Damir Kračun, Xinpei Chen, Sabine Bauer, Joachim P. Schmitt, Florian Flenkenthaler, Josh Gorham, Christopher N. Toepfer, David Potěšil, Pavel Hruška, Zbyněk Zdráhal, Zsuzsanna Mayer, Mathieu Klop, Luisa Lehmann, Yishi Qin, Laura Papanakli, Nadine Spielmann, Alessandra Moretti, Thomas Fröhlich, Peter Ewert, Stefan Holdenrieder, Jonathan G. Seidman, Christine E. Seidman, Agnes Görlach, Cordula M. Wolf   +30 more
doaj   +1 more source

Epidemiology of congenital heart defects in France from 2013 to 2022 using the PMSI-MCO (French Medical Information System Program in Medicine, Surgery, and Obstetrics) database.

PLoS ONE
BackgroundCongenital heart defects are common and occur in approximately 0.9% of births. In France, the registries cover approximately 20% of the population but not the entirety of France; therefore, we aimed to update the incidence data for congenital ...
Gurvan Bourdon, Xavier Lenne, François Godart, Laurent Storme, Didier Theis, Damien Subtil, Amelie Bruandet, Thameur Rakza   +7 more
doaj   +1 more source

Intraoperative sodium range affects white matter microstructure in neonatal congenital heart disease

International Journal of Cardiology Congenital Heart Disease
Background: Intraoperative sodium changes and new postoperative white matter injury are prevalent in neonates with congenital heart disease (CHD) who undergo cardiopulmonary bypass surgery. Rapid sodium correction in hyponatremia is associated with white
Mirthe E.M. van der Meijden, Kim van Loon, Maaike Nijman, Hanna Talacua, Johannes M.P.J. Breur, Joppe Nijman, Nathalie H.P. Claessens, Serena J. Counsell, Manon J.N.L. Benders, Alexandra F. Bonthrone   +9 more
doaj   +1 more source