Results 181 to 190 of about 2,203,451 (295)

The Moral (Un)Desirability of New Biomedical Technologies as Potential Techno‐Fixes

Bioethics, EarlyView.
ABSTRACT The techno‐fix argument, used to argue against technological interventions that address the consequences of social problems instead of their underlying causes, is increasingly invoked in biomedical discussions. However, especially in biomedicine, the techno‐fix argument remains conceptually underdeveloped.
Lieke van Kempen, Martine C. de Vries, Nienke de Graeff   +2 more
wiley   +1 more source

Introduction to the 2026 National Birth Defects Prevention Network Virtual Issue. [PDF]

Birth Defects Res
Fisher SC, Nembhard WN.
europepmc   +1 more source

The Health, Wellbeing and Health Service Use of Women Attempting or Planning Pregnancy: A Nationwide Cross‐Sectional Survey of Australian Women

Birth, EarlyView.
ABSTRACT Background Health and wellbeing during the preconception period influence maternal and child health outcomes. We describe the sociodemographic and health characteristics of Australian women currently attempting pregnancy or planning to conceive in the next 12 months, compared with other women of reproductive age, to identify opportunities for ...
Amie Steel, Danielle Schoenaker, Joanna Harnett, Jon Adams   +3 more
wiley   +1 more source

Congenital Heart Diseases in Children: A Narrative Analysis of Early Diagnosis, Clinical Management, and Long-Term Outcomes. [PDF]

Cureus
Nabi MSM, Barik RR, Sharma A, Garima, Sharma C, I VR, Goud AR.   +6 more
europepmc   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

British Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi, Nandakumar Natarajan, Kathryn E. Dickerson, Richard A. Voit   +3 more
wiley   +1 more source

Trends of congenital rubella syndrome among infants (0-11 months old) in India: a multicentre hospital-based sentinel surveillance (2016-2025). [PDF]

Lancet Reg Health Southeast Asia
Shanmugasundaram D, Verma S, Tripathi S, Dwibedi B, Singh K, Mahantesh S, Malik S, Singh H, Santhanam S, Mondal N, Sinha MK, Jain M, Chowdhary BK, Vishwanathan R, Pawar SD, Sapkal G, Som TK, Kumar A, Pati S, Datta S, Ramasamy S, Rajendran PP, Singh MP, Ratho RK, Shukla S, Mishra B, Gadepalli R, Nag VL, Munivenkatappa A, Biswas D, Devara SM, Vannavada SR, Abraham AM, Dhodapkar R, Ray R, Pati BK, Sreenivasan P, Geetha S, Bavdekar A, Prakash J, Ray J, Gupta M, Rohit MK, Sankhyan N, Gupta PC, Kumar P, Munjal SK, Naganur SH, Sharma A, Agarwal S, Verma V, Sahoo A, Gupta N, Priyanka P, Augustine AM, John D, Kumar M, Bethou A, Alexander A, Anantharaj A, Kasturi N, Gupta D, Chowdhoury SR, Mukherjee S, Basu S, Prasad A, Raj A, Bhavana K, Nalavade U, Rane SV, Murhekar M.   +70 more
europepmc   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

LACHT syndrome with branchial cyst in a female infant; case report and review of literature. [PDF]

BMC Pediatr
Osman A, Eldesoky T, Eksail S, Salman H, Salman Z.   +4 more
europepmc   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle, Christine Lefevre, Simon Boussion, Cindy Colson, Iva Gueorguieva, Francois Marcelli, Anne Laure Barbotin, Pascal Pigny, Hamza Benderradji, Clara Leroy   +9 more
wiley   +1 more source

Effectiveness of Recombinant Human Growth Hormone Therapy in Small‐for‐Gestational‐Age Children With Short Stature: A Stratified Analysis Based on Genetic Variant Status

Clinical Endocrinology, EarlyView.
ABSTRACT Objective This study aimed to evaluate the impact of pathogenic genetic variants on growth outcomes following 3 years of recombinant human growth hormone (rhGH) therapy in children born small for gestational age with persistent short stature (SGA‐SS). Design A retrospective cohort study.
Sanghee Park, Yena Lee, Hwal Rim Jeong, Eun Young Kim, Eu‐seon Noh, Hye young Jin, Eun Byul Kwon, Hye Jin Lee, Young‐Jun Seo, Young Suk Shim, Su Jin Kim, Ji‐Eun Lee, Nan Young Kim, Sangkyoon Hong, Min Jae Kang, Il Tae Hwang   +15 more
wiley   +1 more source