Results 111 to 120 of about 14,472,131 (409)

Treating the patient not just the disease? : Delving deeper into the possible link between affective disorders and coronary heart disease through statistical analysis of a random sample of Maltese people [PDF]

, 2014
Background: Ischemic heart disease is the leading cause of death in Males in Malta and globally. Affective disorders are the commonest psychological problem.
Calleja, Neville, Debono, David
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A nomogram integrating the CHA2DS2-VASc score for predicting atrial fibrillation recurrence following catheter ablation

BMC Cardiovascular Disorders
Objective This study aimed to explore the predictive efficacy of a nomogram based on the congestive heart failure, hypertension, age, diabetes mellitus, prior stroke, transient ischemic attack or thromboembolism, vascular disease, age, and sex category ...
Lin-Qian Jiang, Yu-Hong Zhong, Xue-Hai Chen, Zhe Xu, Ke-Zeng Gong, Fei-Long Zhang   +5 more
doaj   +1 more source

Diabetic Heart Disease

British Journal of Multidisciplinary and Advanced Studies, 2020
Changes in the human environment, behavior, and lifestyle are contributing to the upsurge in the incidence of diabetes. However, better management has resulted in a longer survival of patients with diabetes, but it is accompanied by long-term chronic complications due to hyperglycemia. Individuals with diabetes most often die of cardiovascular disease (
P Ram Mohan Reddy, R Vinola, T Samyuktha, D Sujin, S Saran Kumar, D Hepcy Kalarani   +5 more
openaire   +1 more source

3D printing is a transformative technology in congenital heart disease [PDF]

, 2018
Survival in congenital heart disease has steadily improved since 1938, when Dr. Robert Gross successfully ligated for the first time a patent ductus arteriosus in a 7-year-old child.
Anwar, Anwar, Barach, Bernhard, Bhatla, Biglino, Biglino, Binder, Boneva, Borrello, Botto, Brown, Bucher, Byrne, Chaowu, Conti, Costello, Dearani, Deferm, Duan, Duan, Erikssen, Fan, Farooqi, Farooqi, Farooqi, Fleming, Fukunishi, Garekar, Gaynor, Gentles, Giamberti, Giannopoulos, Giroud, Gosnell, Grant, Green, Hadeed, Hermsen, Hoffman, Holst, Holst, Hu, Jacobs, Jana, Javan, Jonas, Kappetein, Kapur, Khairy, Kiraly, Kirklin, Kolli, Kotsis, Kung, Lee, Lee, Little, Lloyd-Jones, Mahle, Mahmood, Mannoor, Maragiannis, Markert, Markstedt, Mashari, Meier, Michael, Mitsouras, Moons, Moore, Morrison, Muraru, Ngan, Noecker, Olivieri, Olivieri, O’Brien, O’Neill, Pentecost, Poterucha, Randazzo, Rehder, Riesenkampff, Ripley, Rodriguez-Paz, Ryan, Saeed, Samuel, Santos dos, Schievano, Schmauss, Shah, Smith, Sodian, Sodian, Sutcliffe, Tabriz, Tack, Taylor, Valverde, VanKoevering, Vukicevic, Vukicevic, Vukicevic, Wang, Wang, Warnes, Warnes, Warnes, Whitlock, Wilasrusmee, Williams, Witschey, Yoo, Yoo, Zopf, Zweifel   +117 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Right Ventricular Pacing and Sensing Function in High Posterior Septal and Apical Lead Placement in Cardiac Resynchronization Therapy

Indian Pacing and Electrophysiology Journal, 2012
Background: The conventional right ventricular (RV) lead position in cardiac resynchronization therapy pacemakers (CRT-P) is the RV apex (RV-A). Little is known about electrophysiological stability and associated complications of pacing leads in RV high ...
H.M. Kristiansen, MD, T. Hovstad, MD, G. Vollan, MD, S. Faerestrand, MD, PhD   +3 more
doaj   +1 more source

Left ventricular clefts - incidental finding or pathologic sign of Wilson's disease? [PDF]

, 2019
Background: Wilson’s disease is an inherited autosomal recessive multi-systemic disorder characterized by reduced excretion and consequently excessive accumulation of copper in different organs, such as the heart. Results: In a prospective controlled
Christoph, Marian, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Pieske, Burkert, Quick, Silvio, Reuner, Ulrike, Speiser, Uwe, Weidauer, Marie, Zhang, Kun   +9 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Association of sodium-glucose cotransporter 2 inhibitors with risk of major adverse cardiovascular events in type 2 diabetes patients with acute coronary syndrome: a propensity score‑matched analysis

Cardiovascular Diabetology
Background This study aimed to investigate the association of sodium-glucose cotransporter 2 inhibitors (SGLT2i) use with cardiovascular (CV) clinical outcomes in type 2 diabetes (T2D) patients with acute coronary syndrome (ACS).
Tao Liu, Zeyuan Fan, Bing Xiao, Chang He, Shicong Wang   +4 more
doaj   +1 more source