Results 141 to 150 of about 6,881,139 (308)

Integrating Clinical Multi-Omics, Machine Learning, and Molecular Docking Strategies to Reveal the Mechanism of Yiqi Huoxue Prescription in the Treatment of Ischemic Heart Failure

Drug Design, Development and Therapy
Jingjing Wei,1 Lijie Qiao,1 Peng Yu,2 Ying Li,3 Xingyuan Li,1 Ming Li,1 Xinfeng Zhu,1 Wenjun Wu,1 Aolong Wang,1 Yilin Zhang,1 Lanxin Li,1 Bin Li,1 Qifei Zhao,1 Rui Yu,1 Yizho Li,1 Zhengwei Dong,1 Shanshan Nie,1 Yongxia Wang,1 Xinlu Wang,1 Mingjun Zhu1 ...
Wei J, Qiao L, Yu P, Li Y, Li X, Li M, Zhu X, Wu W, Wang A, Zhang Y, Li L, Li B, Zhao Q, Yu R, Li Y, Dong Z, Nie S, Wang Y, Wang X, Zhu M   +19 more
doaj  

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Heart Failure in Adult Congenital Heart Disease. [PDF]

Methodist Debakey Cardiovasc J
Richardson JN, Martin CM.
europepmc   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

National Heart Disease and Stroke Prevention Program evaluation guide

"Background In 1998, the U.S. Congress provided funding for the Centers for Disease Control and Prevention (CDC) to initiate a national, state-based program, the Heart Disease and Stroke Prevention (HDSP) Program.

core  

Sensitivity of Administrative Coding for Heart Disease in Pregnancy. [PDF]

Clin Epidemiol
Amarasinghe GS, Ranasinghe I, Pidgeon T, Lust KMC, Kularatna S, Malatzky C, Parsonage W.   +6 more
europepmc   +1 more source

Carcinoid Heart Disease

Journal of the Advanced Practitioner in Oncology
Carcinoid heart disease (CHD) is a rare but potentially life-threatening sequela of advanced neuroendocrine neoplasm with carcinoid syndrome. These tumors can secrete vasoactive substances of which serotonin is the most prevalent. Carcinoid heart disease typically involves the right-sided heart valves and eventually leads to right heart failure ...
openaire   +2 more sources

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source