Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure [PDF]
Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and ...
Ashley, Euan A. +34 more
core +2 more sources
Background Emerging evidence suggests that patients with coronary artery disease carry an increased risk of developing malignancy, with deleterious effects on long-term prognosis. Our aim was to ascertain whether baseline plasma lipid levels during acute
Giuseppe Berton +5 more
doaj +1 more source
KATP channel dependent heart multiome atlas
Plasmalemmal ATP sensitive potassium (KATP) channels are recognized metabolic sensors, yet their cellular reach is less well understood. Here, transgenic Kir6.2 null hearts devoid of the KATP channel pore underwent multiomics surveillance and systems ...
D. Kent Arrell +8 more
doaj +1 more source
Cultural challenges to secondary prevention: Implications for Saudi women [PDF]
Like other highly developed countries, cardiovascular disease (CVD) and coronary heart disease (CHD) are major health problems in Saudi Arabia. The aetiology of cardiovascular disease (CVD) burden within the Saudi population is similar to Western ...
Clark, Robyn +3 more
core +2 more sources
Interdisciplinary three-step strategy to treat aortic stenosis and coronary artery disease in a patient with end-stage chronic obstructive pulmonary disease [PDF]
Background: Valvular aortic stenosis is a common disease in the elderly, often in multimorbid patients. It is often associated with coronary artery disease and peripheral artery disease.
Beiras Fernández, Andrés +6 more
core +2 more sources
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
STRIDE (Stanford Translational Research Integrated Database Environment) is a research and development project at Stanford University to create a standards-based informatics platform supporting clinical and translational research.
D. Mozaffarian +39 more
semanticscholar +1 more source
Atypical Atrial Tachycardia in a Newborn – a Case Report
We present the case of a neonatal patient with atrial tachycardia with unusual characteristics – abrupt onset and cessation, non-responsiveness to overdrive, termination by direct cardio-version – in association with an ostium secundum-type atrial septal
Gábor-Miklósi Dorottya +6 more
doaj +1 more source
Predicting prolonged intensive care unit stay following surgery in adults with Tetralogy of Fallot
Background: As more patients with congenital heart disease survive into adulthood, the number of patients with tetralogy of Fallot (TOF) has also increased.
Yuta Kuwahara +8 more
doaj +1 more source
Eigenhearts for diagnosis of congestive heart failure (CHF) [PDF]
Common cardiac diseases such as cardio-myopathy, coronary artery diseases, and valve diseases, result in abnormal myocardial movement, which could eventually lead to heart failure, also called congestive heart failure (CHF). CHF is a disease in which the
Ahanathapillai, Vijayalakshmi +1 more
core +1 more source
Carcinoid heart disease: [PDF]
A 72-year-old gentleman presented with right heart failure (RHF) from tricuspid insufficiency. He also noted episodes of diarrhoea and flushing. Echocardiogram showed severe tricuspid regurgitation (TR) with thickened tricuspid leaflets ( Panel A ).
Dashwood, Alexander +2 more
openaire +3 more sources

