Results 71 to 80 of about 6,881,139 (308)

Case Report: Analysis of the missed diagnosis of atrial septal defect with partial pulmonary vein dual drainage

Frontiers in Cardiovascular Medicine
ObjectiveThis study aimed to investigate the reasons for the misdiagnosis of a case of atrial septal defect (ASD) complicated by partial anomalous pulmonary venous connection (PAPVC) to improve clinical diagnosis accuracy in similar cases.MethodsThe ...
Chi-heng Zhou, Yuan-yuan Zhang, Qun-shan Shen   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: Prospective, population based study of British men [PDF]

, 2005
Objective: To examine trends over time in rates of different forms of diagnosed coronary heart disease among British men, during a period in which mortality due to coronary heart disease has been declining.
Morris, RW, Lampe, Fiona C, Lampe, FC, Walker, Mary, Whincup, Peter H, Whincup, PH, Morris, Richard W, Walker, M, Gerald Shaper, A, Shaper, A Gerald   +9 more
core   +1 more source

Case Report: Sustained ventricular arrhythmia in a child supported by a Berlin heart EXCOR ventricular assist device

Frontiers in Transplantation
Mechanical circulatory support is an established therapy to support failing hearts as a bridge to transplantation. Although tolerated overall, arrhythmias may occur after ventricular assist device implantation and can complicate patient management.
Diego Lineker Marquetto Silva, Stephanie Ondracek Lemouche, Tatiane Yukari Takahashi, Isadora de Campos Zanon, Adailson Siqueira, Desiree Machado, Estela Azeka, Sissy Lara de Melo   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Impaired cardiac autonomic nervous control after cardiac bypass surgery for congenital heart disease [PDF]

, 2009
We undertook a study to describe changes in heart rate variability (HRV) postoperatively in children undergoing cardiac bypass surgery for congenital heart disease (CHD).
McGlone, Laura, Financial Support Department of Cardiac Surgery and Cardiology, The Royal Hospital for Sick Children, Yorkhill, Glasgow (Funder), Patel, Neil, Danton, Mark D., , Financial Support Department of Cardiac Surgery and Cardiology,, Young, David   +5 more
core   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Surveillance and evaluation data resource guide for heart disease and stroke prevention programs [PDF]

High blood pressure, high sodium intake, high cholesterol, and smoking continue to put more people at risk of heart disease and stroke. To address these risk factors, the CDC focuses on the ABCS of heart disease and stroke prevention\u2014appropriate ...

core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Burden of heart disease in Ohio 2009

, 2010
Title from PDF cover; author statement from p. 2 of cover (viewed on May 19, 2011).; "Created: 1/6/2010 ... ; Modified: 1/11/2010 ..."--Document properties screen.; Includes bibliographical references.Key findings -- Risk factors, prevalence and access ...
DeFiore-Hyrmer, Jolene.
core