Results 291 to 300 of about 2,491,673 (353)

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Circulating 25-Hydroxyvitamin D Levels During Pregnancy and Risk of Congenital Heart Diseases: Multivariable and Mendelian Randomization Analyses Using 3 Birth Cohorts. [PDF]

J Am Heart Assoc
Walker KC, Specht IO, Hjortdal V, Christesen HT, Heitmann BL, Santorelli G, West J, Magnus P, Njølstad PR, Corfield EC, Havdahl A, Magnus M, Taylor K, Lawlor DA.   +13 more
europepmc   +1 more source

Uniting 4D Printing and Melt Electrowriting for the Enhancement of Regenerative Small Diameter Vascular Grafts

Advanced Healthcare Materials, EarlyView.
A hybrid 4D printing strategy enables the fabrication of shape‐morphing, mechanically reinforced tubular constructs for vascular tissue engineering. By combining alginate‐methylcellulose hydrogels with melt electrowritten polycaprolactone fibers and protein‐based functionalization, this platform supports spatially organized co‐cultures of fibroblasts ...
Max von Witzleben, Akvilė Gasiūnaitė, Marlene Ihle, Ashwini Rahul Akkineni, Kathleen Schütz, Tilman Ahlfeld, Michael Gelinsky, Anja Lode, Sarah Duin   +8 more
wiley   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

ESC Heart Failure
Jan Biegus, Piort Gajewski, Piotr Ponikowski   +2 more
doaj   +1 more source

Kernel random forest with black hole optimization for heart diseases prediction using data fusion. [PDF]

PeerJ Comput Sci
Alluhaidan AS, Maashi M, Negm N, Alotaibi SD, Alzahrani IR, Salama AS.   +5 more
europepmc   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source

From ECG to Imaging: Challenges in the Diagnosis of Adult Congenital Heart Diseases. [PDF]

J Clin Med
Crișan S, Băghină RM, Luca S, Pătru O, Lazăr MA, Văcărescu C, Rus M, Cozma D, Gaiță D, Luca CT.   +9 more
europepmc   +1 more source

The Critical Role of Comorbidities in Managing Heart Failure with Preserved Ejection Fraction (HFpEF)

ESC Heart Failure
Piotr Gajewski, Robert Zymlinski, Jan Biegus   +2 more
doaj   +1 more source

Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia. [PDF]

Exp Physiol
Heath A, von Alvensleben I, Spielvogel JA, Freudenthal P, Trapp J, Noya I, Gálvez M, Mendizábal F, Gonzales M, Apaza C, Sanga L, Mc Cann E, Julian CG.   +12 more
europepmc   +1 more source

Identifying risk factors associated with the health-related quality of life for coronary heart diseases elderly using association rule mining. [PDF]

Sci Rep
Wang C, Zhang Y, Wang S, Wang Y, Shen Y, Ding H.   +5 more
europepmc   +1 more source