Circulating 25-Hydroxyvitamin D Levels During Pregnancy and Risk of Congenital Heart Diseases: Multivariable and Mendelian Randomization Analyses Using 3 Birth Cohorts. [PDF]
Walker KC+13 more
europepmc +1 more source
Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source
Identifying risk factors associated with the health-related quality of life for coronary heart diseases elderly using association rule mining. [PDF]
Wang C+5 more
europepmc +1 more source
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu+5 more
wiley +1 more source
Loop diuretics in heart failure: The objective markers to guide the therapy are needed
Jan Biegus+2 more
doaj +1 more source
Cardiac macrophages in maintaining heart homeostasis and regulating ventricular remodeling of heart diseases. [PDF]
Kang M+7 more
europepmc +1 more source
Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley +1 more source
Kernel random forest with black hole optimization for heart diseases prediction using data fusion. [PDF]
Alluhaidan AS+5 more
europepmc +1 more source
Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia. [PDF]
Heath A+12 more
europepmc +1 more source