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Heart failure

The Lancet, 2009
Despite advances in management of heart failure, the condition remains a major public-health issue, with high prevalence, poor clinical outcomes, and large health-care costs. Risk factors are well known and, thus, preventive strategies should have a positive effect on disease burden.
Henry, Krum, William T, Abraham
openaire   +4 more sources

The Heart in Heart Failure

Annals of Internal Medicine, 1968
Abstract The inevitable occurrence of congestive heart failure in the course of chronic cardiac disease has led to much speculation concerning a possible defect in intrinsic contractile performance...
openaire   +2 more sources

HEART FAILURE

Cardiology Clinics, 1999
Heart failure is predominantly a disorder of older adults, and to a large extent the epidemiology of heart failure reflects the convergence of age-related changes in the cardiovascular system and the rising prevalence of age-related cardiovascular diseases.
openaire   +2 more sources

Adiponectin in Heart Failure

Future Cardiology, 2020
The adipose tissue, apart from storing energy, plays a role of an endocrine organ. One of the most important adipokines secreted by adipose tissue is adiponectin, which is also produced by cardiomyocytes and connective tissue cells within the heart. Adiponectin is known for its beneficial effect on the metabolism and cardiovascular system and its low ...
Hubert Mado   +3 more
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Arrhythmogenesis in Heart Failure

Journal of Cardiovascular Electrophysiology, 2001
Arrhythmogenesis in Heart Failure. In a rabbit model of heart failure produced by combined pressure and volume overload, nonsustained ventricular tachycardias developed in 15 of 23 failing rabbits. Sinus rate was increased in rabbits dying suddenly, but was decreased in survivors. This also was true in isolated preparations.
Janse, M. J.   +7 more
openaire   +2 more sources

Heart Failure

The Journal of Continuing Education in Nursing, 2007
Heart failure is the most common reason for hospital admission in the United States. All nurses, regardless of their specialty, should be familiar with this clinical syndrome. This column describes the pathophysiology and treatment of heart failure.
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Testosterone and heart failure

Endocrine, 2012
Testosterone deficiency is a generalized phenomenon seen in the course of chronic heart failure (CHF). Reduction in circulating testosterone level is a predictor of deterioration of functional capacity over time, underscoring the role of testosterone deficiency in CHF.
Volterrani, M   +2 more
openaire   +3 more sources

Pathophysiology of Heart Failure

Mineral and Electrolyte Metabolism, 1999
Heart failure is a leading cause of mortality and morbidity in Western countries. Common etiology is mostly represented by ischemic and hypertensive heart disease. Clinically, heart failure can be defined as an impaired cardiac performance, unable to meet the energy requirements of the periphery.
CHIARIELLO M, PERRONE FILARDI, PASQUALE
openaire   +3 more sources

Frailty in Heart Failure

Current Heart Failure Reports, 2014
Considering the increasing age of individuals affected with heart failure (HF), a specific approach to their treatment is required, with more attention paid to geriatric conditions such as poor mobility, multiple disabilities, and cognitive impairment. Frailty is a distinct biological syndrome reflecting decreased physiologic reserve and resistance to ...
Izabella, Uchmanowicz   +4 more
openaire   +2 more sources

‘Mitotherapy’ for Heart Failure

Trends in Molecular Medicine, 2016
Abnormalities in mitochondrial dynamics along with those for the molecular mediators involved are presently being viewed with increased interest in the field of cardiovascular disease. Recent research highlights OPA1, a dynamin-like GTPase mediating mitochondrial fusion, as well as the 'mitoproteases' OMA1 and YME1L, as potential therapeutic targets ...
Sanchis Gomar, Fabian   +2 more
openaire   +4 more sources

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