Rehospitalization burden and morbidity risk in patients with heart failure with mid‐range ejection fraction [PDF]
Aims Heart failure with mid‐range ejection fraction (HFmrEF) has been proposed as a distinct HF phenotype, but whether patients on this category fare worse, similarly, or better than those with HF with reduced EF (HFrEF) or preserved EF (HFpEF) in terms ...
Enrique Santas +9 more
doaj +2 more sources
Use of angiotensin receptor blocker is associated with improved 1 year mortality in heart failure with mid‐range ejection fraction [PDF]
Aims Current evidence about the effect of angiotensin receptor blocker (ARB) on the outcome of heart failure with mid‐range ejection fraction (HFmrEF) is lacking.
Bin Wang +6 more
doaj +2 more sources
Spironolactone use is associated with improved outcomes in heart failure with mid‐range ejection fraction [PDF]
Aims Spironolactone has been shown to improve outcomes in patients with heart failure (HF) with reduced ejection fraction (EF). We investigated whether the discharge use of spironolactone could be associated with better long‐term outcomes among patients ...
Nobuyuki Enzan +6 more
doaj +2 more sources
Heart failure with mid-range or mildly reduced ejection fraction [PDF]
Left ventricular ejection fraction (EF) remains the major parameter for diagnosis, phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure guidelines introduced a third EF category for an EF of 40-49%, defined as heart failure with mid-range EF (HFmrEF).
Gianluigi Savarese, , Lars H Lund
exaly +4 more sources
Secondary valve regurgitation in patients with heart failure with preserved ejection fraction, heart failure with mid-range ejection fraction, and heart failure with reduced ejection fraction. [PDF]
Abstract Secondary mitral regurgitation and secondary tricuspid regurgitation due to heart failure (HF) remain challenging in almost every aspect: increasing prevalence, poor prognosis, notoriously elusive in diagnosis, and complexity of therapeutic management.
Bartko PE +8 more
europepmc +5 more sources
Heart Failure with Mid-range Ejection Fraction: Lessons from CHARM. [PDF]
The newly defined category of heart failure (HF) with mid-range ejection fraction (HFmrEF; EF 40–49 %) is beginning to be characterised but little is known about the potential for treating it. Trials and observational studies suggest that standard therapy for HF with reduced ejection fraction (HFrEF; EF <40 %) may also offer some benefit to patients
Lund LH.
europepmc +3 more sources
Heart Failure with Mid-range Ejection Fraction——a Comprehension of the Disease [PDF]
Heart failure is the final main battlefield of various cardiovascular diseases with huge harm, which can cause all kinds of arrhythmias and even sudden cardiac death. The 2016 ESC guidelines formally define heart failure with mid-range ejection fraction (
RUAN Zheng, HUANG Jianyu, JIANG Wencai, CHEN Meixiang, QIN Changyu, XU Lin
doaj +2 more sources
Heart failure with mid-range ejection fraction: Current evidence and uncertainties
Heart failure (HF) with mid-range ejection fraction (HFmrEF) has been conceptualized by the European Society of Cardiology guidelines with the aim of stimulating research to fill a gap in knowledge: whether such a condition exists as a distinct ...
Raffaele Martone +2 more
doaj +5 more sources
Trajectories of Waist-to-Hip Ratio and Adverse Outcomes in Heart Failure with Mid-Range Ejection Fraction [PDF]
Background: Waist-to-hip ratio (WHR) is a strong predictor of mortality in patients with heart failure (HF). However, common WHR trajectories are not well established in HF with mid-range ejection fraction (HFmrEF) persons, and their relationship to ...
Feng Gao +5 more
doaj +2 more sources
Is heart failure with mid range ejection fraction (HFmrEF) a distinct clinical entity or an overlap group? [PDF]
Background: The new category of heart failure (HF), Heart Failure with mid range Ejection Fraction (HFmrEF) has recently been proposed with recent publications reporting that HFmrEF represents a transitional phase.
Jessica Webb +14 more
doaj +2 more sources

