Predictors and outcomes of heart failure with mid-range ejection fraction. [PDF]
Aims While heart failure with preserved (HFpEF) and reduced ejection fraction (HFrEF) are well described, determinants and outcomes of heart failure with mid‐range ejection fraction (HFmrEF) remain unclear. We sought to examine clinical and biochemical predictors of incident HFmrEF in the community.
Bhambhani V +36 more
europepmc +8 more sources
Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction [PDF]
In this study, the authors used biomarker profiles to characterize differences between patients with acute heart failure with a midrange ejection fraction (HFmrEF) and compare them with patients with a reduced (heart failure with a reduced ejection fraction [HFrEF]) and preserved (heart failure with a preserved ejection fraction [HFpEF]) ejection ...
Tromp, Jasper +16 more
core +19 more sources
Heart failure with mid-range or mildly reduced ejection fraction [PDF]
Left ventricular ejection fraction (EF) remains the major parameter for diagnosis, phenotyping, prognosis and treatment decisions in heart failure. The 2016 ESC heart failure guidelines introduced a third EF category for an EF of 40-49%, defined as heart failure with mid-range EF (HFmrEF).
Gianluigi Savarese +3 more
openaire +5 more sources
Mortality from Heart Failure with Mid-Range Ejection Fraction. [PDF]
The prognostic importance of the classification 'heart failure (HF) with mid-range ejection fraction (EF)' remains uncertain.To analyze the clinical characteristics, comorbidities, complications, and in-hospital and late mortality of patients classified as having HF with mid-range EF (HFmrEF - EF: 40%-49%), and to compare them to those of patients with
Dutra GP +6 more
europepmc +3 more sources
Spironolactone use is associated with improved outcomes in heart failure with mid‐range ejection fraction [PDF]
Aims Spironolactone has been shown to improve outcomes in patients with heart failure (HF) with reduced ejection fraction (EF). We investigated whether the discharge use of spironolactone could be associated with better long‐term outcomes among patients ...
Nobuyuki Enzan +6 more
doaj +2 more sources
Heart failure with mid-range ejection fraction in CHARM: characteristics, outcomes and effect of candesartan across the entire ejection fraction spectrum. [PDF]
AIMS: We tested the hypothesis that candesartan improves outcomes in heart failure (HF) with mid-range ejection fraction [HFmrEF; ejection fraction (EF) 40-49%].
Borlaug +25 more
core +4 more sources
Secondary valve regurgitation in patients with heart failure with preserved ejection fraction, heart failure with mid-range ejection fraction, and heart failure with reduced ejection fraction. [PDF]
Abstract Secondary mitral regurgitation and secondary tricuspid regurgitation due to heart failure (HF) remain challenging in almost every aspect: increasing prevalence, poor prognosis, notoriously elusive in diagnosis, and complexity of therapeutic management.
Bartko PE +8 more
europepmc +5 more sources
Heart Failure with Mid-range Ejection Fraction: Lessons from CHARM. [PDF]
The newly defined category of heart failure (HF) with mid-range ejection fraction (HFmrEF; EF 40–49 %) is beginning to be characterised but little is known about the potential for treating it. Trials and observational studies suggest that standard therapy for HF with reduced ejection fraction (HFrEF; EF <40 %) may also offer some benefit to patients
Lund LH.
europepmc +3 more sources
Heart failure with mid-range ejection fraction. Where are we today? [PDF]
Bulgarian Society of Cardiology adhere to the European Guidelines on Heart Failure (HF). The fi nalized studies and many debates and analyses after 2016 are prerequisite to creation of a new guideline for diagnosis and management on these patients.
Tzvetana Katova
doaj +5 more sources
Heart failure with mid-range ejection fraction: Current evidence and uncertainties
Heart failure (HF) with mid-range ejection fraction (HFmrEF) has been conceptualized by the European Society of Cardiology guidelines with the aim of stimulating research to fill a gap in knowledge: whether such a condition exists as a distinct ...
Raffaele Martone +2 more
doaj +5 more sources

