Results 101 to 110 of about 2,466,541 (396)

Left-Sided Angiosarcoma of Heart: A Rare Case [PDF]

Journal of Tehran University Heart Center, 2009
A 22-year-old man presented with exertional dyspnea commencing one month prior to his admission. Echocardiography revealed a non-homogenous mass, and the pathology examination of the pericardial biopsy was compatible with angiosarcoma.
Maryam Moshkani Farahani, Davood Kazemi Saleh, Yahya Dadjoo, Bahram Pishgoo   +3 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Massive pericardial effusion as a manifestation of cardiac angiosarcoma

Heart Vessels and Transplantation
Objective: Pericardial effusion, resulting from various conditions including infections, malignancies, and post-operative complications, can lead to significant diagnostic challenges, especially in cases where hemopericardium is present.
Ihor Romaniuk, Andriy Mangov, Sofia Vyshynska, Oleh Kobziev, Uliana Pidvalna   +4 more
doaj   +1 more source

Focusing on the premature death of redeployed miners in China: an analysis of cause-of-death information from non-communicable diseases

Globalization and Health, 2019
Background Reducing premature deaths is an important step towards achieving the World Health Organization’s sustainable development goal. Redeployed miners are more prone to disease or premature death due to the special occupational characteristics.
Wei Xian, Bing Han, Leizhen Xia, Yining Ma, Haodi Xu, Lu Zhang, Li Li, Hongbo Liu   +7 more
doaj   +1 more source

Hematopoietic alterations in chronic heart failure patients by somatic mutations leading to clonal hematopoiesis

Haematologica, 2019
Acquired somatic mutations in genes associated with myeloid neoplasms have been recently identified in blood cells of elderly individuals without any hematologic abnormalities, leading to clonal blood cell expansion.
Lena Dorsheimer, B. Assmus, T. Rasper, Christina A. Ortmann, K. Abou-El-Ardat, Katharina Kiefer, Jedrzej Hoffmann, F. Seeger, H. Bonig, S. Dimmeler, A. Zeiher, M. Rieger   +11 more
semanticscholar   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Heart Abnormality Detection from Heart Sound Signals using MFCC Feature and Dual Stream Attention Based Network [PDF]

arXiv, 2022
Cardiovascular diseases are one of the leading cause of death in today's world and early screening of heart condition plays a crucial role in preventing them. The heart sound signal is one of the primary indicator of heart condition and can be used to detect abnormality in the heart. The acquisition of heart sound signal is non-invasive, cost effective
arxiv  

The Correlation of Plasma 25-Hydroxyvitamin D Deficiency With Risk of Breast Neoplasms: A Systematic Review

Iranian Journal of Cancer Prevention, 2016
Context Breast cancer has been considered as one of the most common types of cancer among the women worldwide, and patients with breast neoplasms have been reported with high prevalence of low serum 25-hydroxyvitamin D levels.
Reza Shekarriz-Foumani, Faezeh Khodaie
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source