Results 141 to 150 of about 3,538,667 (295)

Usefulness of heart measures in flight simulation [PDF]

The results of three studies performed at the NASA Langley Research Center are presented to indicate the areas in which heart measures are useful for detecting differences in the workload state of subjects.
Bonadies, Gregory A., Comstock, J. Raymond, Jr., Harris, Randall L., Sr.   +2 more
core   +1 more source

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 805-820, April 2025.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro, Neetha Paul Eduthan, Mellad M. Khoshnood, Saba Jafarpour, Natalie K. Boyd, Benjamin N. Vogel, Lina Nguyen, Lilia Kazerooni, Eleanor Britton, Hannah R. Lyford, Matthew D. Galbraith, Angela L. Rachubinski, Joaquin M. Espinosa   +12 more
wiley   +1 more source

Heart Rate Variability, Deceleration Capacity of Heart Rate, and Death: A Veteran Twins Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Autonomic function can be measured noninvasively using heart rate variability (HRV), which indexes overall sympathovagal balance. Deceleration capacity (DC) of heart rate is a more specific metric of vagal modulation.
Minxuan Huang, Amit J. Shah, Rachel Lampert, Donald L. Bliwise, Dayna A. Johnson, Gari D. Clifford, Richard Sloan, Jack Goldberg, Yi‐An Ko, Giulia Da Poian, Erick A. Perez‐Alday, Zakaria Almuwaqqat, Anish Shah, Mariana Garcia, An Young, Kasra Moazzami, J. Douglas Bremner, Viola Vaccarino   +17 more
doaj   +1 more source

Right‐sided vagus nerve stimulation: Worldwide collection and perspectives

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 565-576, March 2025.
Abstract Objective Vagus nerve stimulation (VNS) is an established therapy for drug‐resistant epilepsy (DRE) and is indicated for implantation on the left vagus nerve‐only. In rare cases right‐sided VNS may be the only option. With only seven published cases in the literature, data on safety and effectiveness of right‐sided VNS is very limited ...
Marc Zanello, Berthold Voges, Ramesh Chelvarajah, Arjune Sen, Željka Petelin Gadže, Guillaume Penchet, Alessandro De Benedictis, Riccardo Fornaro, Masaki Iwasaki, Keiya Iijima, Elena Jiltsova, Goran Mrak, Sami Barrit, Alessandro Moiraghi, Andrea Landi, Marcus Neale, Shailendra Magdum, François Caire, Bertrand Godet, Philippe Domenech, Raphael Gaillard, Marc Guenot, Jason Labuschagne, Alexandre Rainha Campos, Herbert Rooijakkers, Riëm El Tahry, Tatiana Von Hertwig Fernandes De Oliveira, Amelia Alvarez‐Sala, Cristina V. Torres, Fernando Vale, Johan Pallud, Romain Carron   +31 more
wiley   +1 more source

Novel pathogenic mtDNA variants in Chinese children with neurological mitochondrial disorders

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 586-601, March 2025.
Abstract Objective Pathogenic variations in the mitochondrial genome are tightly linked to neurological mitochondrial disorders in children. However, the mutation spectrum of mitochondrial DNA (mtDNA) in the Chinese population remains incomplete. Therefore, the primary objective of our study was to comprehensively characterize pathogenic mtDNA variants
Zhimei Liu, Kexin Pan, Mingzhao Wang, Yijun Jin, Wenxin Yang, Keer Chen, Chaolong Xu, Xin Duan, Ying Zou, Changhong Ren, Lifang Dai, Suzhou Zhao, Ya Wang, Lijun Shen, Fang Fang, Hezhi Fang   +15 more
wiley   +1 more source

Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome

Annals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 724-736, April 2025.
Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si, Song Xue, Xin Zhou, Ya‐Nan Guo, Wen‐Yu Du, Yang Qu, Xin Sun, Zhen‐Ni Guo   +7 more
wiley   +1 more source

Classification of Short Segment Pediatric Heart Sounds Based on a Transformer-Based Convolutional Neural Network [PDF]

arXiv
Congenital anomalies arising as a result of a defect in the structure of the heart and great vessels are known as congenital heart diseases or CHDs. A PCG can provide essential details about the mechanical conduction system of the heart and point out specific patterns linked to different kinds of CHD.
arxiv  

The burden of intracranial atherosclerosis on cerebral small vessel disease: A community cohort study

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah, Heng Du, Wenjie Yang, Huixing Zeng, Jason Tsz Lok Chan, Michael Lung Cheung Lo, Xiangyan Chen   +6 more
wiley   +1 more source

Music Interventions in Hyperacute and Acute Stroke Patients: A Randomized Controlled Pilot Feasibility Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher, Allison Edberg, Ronald Grifka, Joan Westendorp, Augusto Elias, Jacquie Knott, Elizabeth Martin, Fazeel Siddiqui   +7 more
wiley   +1 more source

Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan, Huaju Tian, Cheng Wu, Yue Zhao, Daiying Zhang, Yujie Zheng, Yuan Li, Xiaoxia Duan   +7 more
wiley   +1 more source