Results 51 to 60 of about 588,028 (287)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Systems and methods for physiological signal enhancement and biometric extraction using non-invasive optical sensors [PDF]

, 2018
A system and method for signal processing to remove unwanted noise components including: (i) wavelength-independent motion artifacts such as tissue, bone and skin effects, and (ii) wavelength-dependent motion artifact/noise components such as venous ...
Nourani, Mehrdad, Yousefi, Rasoul
core   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Real-Time Heart Rate Estimation Using a Standard Camera

Proceedings of the International Conference on Applied Innovations in IT
Health indicators are among the most important ways to assess health status and predict sudden health relapses. Non-contact health monitoring is critical for overcoming limitations of traditional vital sign measurement methods, such as infection risks ...
Ali Sameer Salim, Abdul Sattar Mohammed Khidhir   +1 more
doaj   +1 more source

Removal of Motion Artifacts in Photoplethysmograph Sensors during Intensive Exercise for Accurate Heart Rate Calculation Based on Frequency Estimation and Notch Filtering

Sensors, 2019
With photoplethysmograph (PPG) sensors showing increasing potential in wearable health monitoring, the challenging problem of motion artifact (MA) removal during intensive exercise has become a popular research topic.
Min Wang, Zhe Li, Qirui Zhang, Guoxing Wang   +3 more
doaj   +1 more source

Heart rate estimation using on-nail wearable photoplethysmography [PDF]

2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Heart Rate (HR) measurements in current wearables are mostly derived from photoplethysmography (PPG). PPG signals have been measured at various locations on the body, however, to date, limited studies have investigated wearable, reflective mode, PPG signals from the finger- and toe- nails.
Binti H. Mohtadzar, Nur Alia Athirah, Balaban, Ertan, Beach, Christopher, Taylor, Paul S., Horne, Robert J., Batchelor, John C., Casson, Alex   +6 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research on Improving the Accuracy of Wearable Heart Rate Measurement Based on a Six-Axis Sensing Device Integrating a Three-Axis Accelerometer and a Three-Axis Gyroscope

Applied Sciences
This study proposes a novel heart rate estimation method that detects subtle cardiac-induced vibrations propagated through the cardiovascular system based on the ballistocardiography (BCG) principle, using a six-axis heart rate sensing device that ...
Jinman Kim, Joongjin Kook
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source