Results 31 to 40 of about 8,140,164 (256)

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Postexercise Heart Rate Recovery in Adults Born Preterm [PDF]

The Journal of Pediatrics, 2019
To evaluate postexercise heart rate recovery (HRR) in adults born preterm.We studied the association between preterm birth and postexercise HRR in 545 adults (267 women) at 23.3 years of age (range 19.9-26.3 years). One hundred three participants were born early preterm (
Karvonen, R. (Risto), Sipola, M. (Marika), Kiviniemi, A. M. (Antti M.), Tikanmäki, M. (Marjaana), Järvelin, M.-R. (Marjo-Riitta), Eriksson, J. G. (Johan G.), Tulppo, M. P. (Mikko P.), Vääräsmäki, M. (Marja), Kajantie, E. (Eero)   +8 more
openaire   +4 more sources

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Resting Heart Rate in Cardiovascular Disease

, 2007
The importance of resting heart rate (HR) as a prognostic factor and potential therapeutic target is not yet generally accepted. Recent large epidemiologic studies have confirmed earlier studies that showed resting HR to be an independent predictor of ...
TARDIF JC, DANCHIN N, FOX K, HEART RATE WORKING GROUP, CAMM AJ, LOPEZ SENDON JL, TAVAZZI L, STEG PG, TENDERA M, BORER JS, Jose L. Lopez Sendon, A. John Camm, Michal Tendera, Kim Fox, Jean-Claude Tardif, Philippe Gabriel Steg, Roberto Ferrari, Nicolas Danchin, Luigi Tavazzi, Jeffrey S. Borer, FERRARI, Roberto   +20 more
core   +1 more source

Heart rate recovery: validation and methodologic issues

Journal of the American College of Cardiology, 2001
The goal of this study was to validate the prognostic value of the drop in heart rate (HR) after exercise, compare it to other test responses, evaluate its diagnostic value and clarify some of the methodologic issues surrounding its use.Studies have highlighted the value of a new prognostic feature of the treadmill test-rate of recovery of HR after ...
Shetler, Katerina, Marcus, Rachel, Froelicher, Victor F, Vora, Shefali, Kalisetti, Damayanthi, Prakash, Manish, Do, Dat, Myers, Jon   +7 more
openaire   +2 more sources

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

The effect of active vs. supine recovery on heart rate, power output, and recovery time [PDF]

, 2013
International Journal of Exercise Science 6(3) : 180-187, 2013. The purpose of this research was to compare the effectiveness of two different post-exercise recovery methods, active and passive, on the heart rate (HR), peak power (PP), average power (AP)
Petrella, John K., Smeltzer, Ryan M., Jung, Alan P., Larson, Lars M.   +3 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Heart Rate Recovery after 6 Min Walk Test In Postmenopausal Women- An Observational Study

, 2019
Background: The Background of Study: Abnormality in heart rate is commonly observed in pre and post-menopausal women. Recovery of the heart rate is early in post-menopausal women which influences there fatigue level.
Dr. Reshma Shete, Pallavi K. Ahire
core   +1 more source