Results 121 to 130 of about 1,464,866 (395)

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

Predict Daily Life Stress based on Heart Rate Variability [PDF]

, 2020
Department of Human Factors EngineeringThe purpose of this study is to investigate the feasibility of predicting a daily mental stress level from analyzing Heart Rate Variability (HRV) by using a Photoplethysmography (PPG) sensor which is integrated in ...
Park, Jongwoo
core  

Mental Workload Alters Heart Rate Variability, Lowering Non-linear Dynamics

Frontiers in Physiology, 2019
Mental workload is known to alter cardiovascular function leading to increased cardiovascular risk. Nevertheless, there is no clear autonomic nervous system unbalance to be quantified during mental stress.
S. Delliaux, A. Delaforge, J. Deharo, Guillaume Chaumet   +3 more
semanticscholar   +1 more source

Plasma Glial Fibrillary Acidic Protein Correlates With Brain Metal Burden in Wilson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuroinflammation driven by extracellular copper contributes to neuronal damage in Wilson's disease (WD). This study investigated the relationship between brain metal burden and peripheral neuroinflammation markers in WD. Methods We conducted a cross‐sectional study involving 89 participants, including patients with WD (n = 63 ...
Sung‐Pin Fan, Ya‐Fang Chen, Cheng‐Hsuan Li, Yih‐Chih Kuo, Ni‐Chung Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Tai‐Chung Tseng, Tung‐Hung Su, Chien‐Ting Hsu, Huey‐Ling Chen, Chin‐Hsien Lin, Yen‐Hsuan Ni   +12 more
wiley   +1 more source

Spectro-Temporal Electrocardiogram Analysis for Noise-Robust Heart Rate and Heart Rate Variability Measurement

IEEE Journal of Translational Engineering in Health and Medicine, 2017
The last few years has seen a proliferation of wearable electrocardiogram (ECG) devices in the market with applications in fitness tracking, patient monitoring, athletic performance assessment, stress and fatigue detection, and biometrics, to name a few.
Diana P. Tobon, Srinivasan Jayaraman, Tiago H. Falk   +2 more
doaj   +1 more source

Spectral Analysis of Heart Rate Variability: Time Window Matters

Frontiers in Neurology, 2019
Spectral analysis of heart rate variability (HRV) is a valuable tool for the assessment of cardiovascular autonomic function. Fast Fourier transform and autoregressive based spectral analysis are two most commonly used approaches for HRV analysis, while ...
Kai Li, Heinz Rüdiger, T. Ziemssen
semanticscholar   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Recurrence Plot Based Measures of Complexity and its Application to Heart Rate Variability Data

, 2002
The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there are several ...
A. Hempelmann, A. L. Goldberger, A. Voss, A. Witt, A. Wolf, Alexander Schirdewan, B. Blasius, C. L. Webber, Jr., E. M. Oblow, H. D. I. Abarbanel, H. V. Huikuri, J. B. Gao, J. B. Gao, J. Kurths, J. Kurths, J. M. Nese, J. O. Diaz, J. P. Zbilut, J.-P. Eckmann, Jürgen Kurths, K. B. Marvel, L. Glass, L. Glass, L. L. Trulla, M. C. Casdagli, N. Wessel, N. Wessel, Niels Wessel, Norbert Marwan, P. E. Rapp, R. Engbert, R. Wackerbauer, S. Guzzetti, U. Schwarz, Udo Meyerfeldt   +34 more
core   +1 more source

Heart rate variability as predictive factor for sudden cardiac death

Aging, 2018
Sudden cardiac death (SCD) represents about 25% of deaths in clinical cardiology. The identification of risk factors for SCD is the philosopher's stone of cardiology and the identification of non-invasive markers of risk of SCD remains one of the most ...
F. Sessa, V. Anna, G. Messina, G. Cibelli, V. Monda, G. Marsala, M. Ruberto, A. Biondi, Orazio Cascio, G. Bertozzi, D. Pisanelli, F. Maglietta, A. Messina, M. Mollica, M. Salerno   +14 more
semanticscholar   +1 more source

Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García, H. Stephan Goedee, Leonard H. van den Berg, Boudewijn T. H. M. Sleutjes   +3 more
wiley   +1 more source