Results 81 to 90 of about 1,713,582 (410)

Cardiac Autonomic Responses during Exercise and Post-exercise Recovery Using Heart Rate Variability and Systolic Time Intervals—A Review

Frontiers in Physiology, 2017
Cardiac parasympathetic activity may be non-invasively investigated using heart rate variability (HRV), although HRV is not widely accepted to reflect sympathetic activity.
S. Michael, K. Graham, G. Davis
semanticscholar   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Hypothetical Control of Heart Rate Variability

Frontiers in Physiology, 2019
In the last three decades, the analysis of heart rate variability by nonlinear methods demonstrated the complexity of cardiovascular regulation. Additionally to the observations of periodic heart rate regulation by the autonomic nervous system, the long ...
Bruce J. West, Malgorzata Turalska
doaj   +1 more source

Heart rate variability and target organ damage in hypertensive patients [PDF]

, 2012
Background: We evaluated the association between linear standard Heart Rate Variability (HRV) measures and vascular, renal and cardiac target organ damage (TOD).
2003 European Society of Hypertension, A Garcia-Garcia, A Kluttig, A Musialik-Lydka, A Shehab, AI Vinik, AL Goldberger, AS Levey, B Dahlof, D Sahn, DH O'Leary, DJ Brotman, DW Kitzman, EB Schroeder, Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, G de Simone, G Ferrari, G Iaccarino, G Lembo, G Mancia, G Martini, G Parati, GN Arbolishvili, JF Thayer, K Jensen-Urstad, K Oikawa, KH Tseng, L Pecchia, L Pecchia, LE Chambless, Leandro Pecchia, LM Ueno, Lomb, M Hollander, M Malik, M Zabalgoitia, MW Lorenz, N De Luca, N de Luca, Nicola De Luca, P Alter, P Chandra, P Hamilton, P Melillo, P Melillo, P Melillo, Paolo Melillo, R Izzo, Raffaele Izzo, RB Devereux, RB Devereux, RF Berntsen, RM Lang, S Kodituwakku, S Yusuf, U Rajendra Acharya, Z Bajko   +56 more
core   +4 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Fetal heart rate and fetal heart rate variability in Lipizzaner broodmares [PDF]

, 2015
Monitoring fetal heart rate (FHR) and fetal heart rate variability (FHRV) helps to understand and evaluate normal and pathological conditions in the foal.
Adamson S. L., Baska-Vincze B., Baska-Vincze B., Boglárka Baska-Vincze, Bowen I. M., Bucca S., Cordero M., Ferenc Baska, Kovács L., Kovács L., Long W. A., Minero M., Mohr E., Nagel C., Nagel C., Nörr J., Ottó Szenci, Palmer J., Reef V. B., Reef V. B., Senger P. L., Van Leeuwen P., Van Leeuwen P., von Borell E., Wheeler T.   +24 more
core   +1 more source

Heart rate and heart rate variability in subjectively reported insomnia [PDF]

Journal of Sleep Research, 2011
According to epidemiological studies, insomnia is associated with cardiovascular mortality. However, it is yet to be determined whether this link is mediated by known cardiovascular risk factors. The current study aimed at investigating the association between primary insomnia, defined as subjectively reported sleep disturbance in the absence of any ...
Spiegelhalder, Kai, FUCHS, LENA, Ladwig, Johannes, Kyle, Simon D., Nissen, Christoph, Voderholzer, Ulrich, Feige, Bernd, Riemann, Dieter   +7 more
openaire   +4 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Heart Rate Variability in Dental Science

Frontiers in Medicine, 2019
Dentistry has made progress as a profession by integration with both medicine and other human sciences, especially when it uses empirical metrics to study process and outcome variables. Notably, progress in our understanding of genomic, biomic, and other
Robert L. Drury, Robert L. Drury, Scott A. Simonetti   +2 more
doaj   +1 more source