Results 121 to 130 of about 2,073,380 (162)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

“Two‐For‐One”: 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2213-2227, November 2026.
ABSTRACT Purpose To generate 4D (3D+time) images of both the heart and lungs using a single volumetric radial free‐breathing bSSFP dual echo acquisition (bSTAR) with two image reconstructions within a single pipeline deployed inline at 0.55 and 1.5 T.
Pierre Daudé, Jordan Taylor, Joseph W. Plummer, Rajiv Ramasawmy, Anastasia Tsakirellis, Joel Moss, W. Patricia Bandettini, Marcus Chen, Adrienne E. Campbell‐Washburn, Ahsan Javed   +9 more
wiley   +1 more source

Surgical Treatment of Amplatzer Embolus in a Secundum Atrial Septal Defect Patient

Journal of Tehran University Heart Center, 2015
A secundum atrial septal defect is the most common congenital heart defect. Transcatheter treatment of secundum atrial septal defects is a popular and less invasive alternative to surgery.
Ahmet Baris-Durukan, Hasan Alper-Gurbuz, Murat Tavlasoglu, Nevriye Salman, Halil Ibrahim-Ucar, Cem Yorgancioglu   +5 more
doaj  

The incidence of atrial septal defects (ASD) as a function of Nipbl genotype in the heart.

, 2016
The incidence of atrial septal defects (ASD) as a function of Nipbl genotype in the heart.
Scott E. Fraser (178546), Shimako Kawauchi (259746), Martha E. Lopez-Burks (259752), Russell E. Jacobs (246394), Benedikt Hallgrimsson (259772), Arthur D. Lander (199741), Anne L. Calof (199737), Hojae Choi (2208850), Heather A. Jamniczky (693523), Rosaysela Santos (259748), Jamie Wikenheiser (3110025)   +10 more
core   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2211-2223, October 2026.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth, Benjamin Kelly, Sheyanth Mohanakumar, Steffen Ringgaard, Yoav Dori, Irene Kibæk Nielsen, Uffe Birk Jensen, Vibeke Elisabeth Hjortdal   +7 more
wiley   +1 more source

Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]

, 2012
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core   +1 more source

Electrocardiographic and Skin Manifestations of Turner Syndrome: Association With Cardiovascular Disease

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2234-2240, October 2026.
ABSTRACT Congenital heart disease (CHD) and dermatologic conditions such as lymphedema and acquired melanocytic nevi (AMN) are common in Turner Syndrome (TS). We hypothesized that abnormalities of cranial neural crest cell derivatives drive the skin and heart manifestations of TS. We conducted joint cardiac and skin examinations of volunteers at a 2023
Sarah Elsaim, Brett Vernier, Van Thi Thanh Truong, Riya T. Patel, Matthew Brown, Martin Chacon Portillo, Megan Rogge, David Rodriguez‐Buritica, Siddharth K. Prakash   +8 more
wiley   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

The commonest mistakes in the treatment of adult patients with congenital heart disease

Zdravniški Vestnik, 2012
Background: General practitioners and medical specialists are seeing adults with congenital heart disease in their everyday practice more frequently than ever.
Jure Dolenc, Mirta Koželj, Katja Prokšelj   +2 more
doaj