Results 21 to 30 of about 2,073,380 (162)

Post-operative atrial fibrillation is influenced by beta-blocker therapy but not by pre-operative atrial cellular electrophysiology [PDF]

, 2006
We investigated whether post-cardiac surgery (CS) new-onset atrial fibrillation (AF) is predicted by pre-CS atrial cellular electrophysiology, and whether the antiarrhythmic effect of beta-blocker therapy may involve pre-CS pharmacological remodeling ...
Marshall, Gillian E., Russell, Julie A., Pau, David, Kane, Kathleen A., Workman, Antony J., Rankin, Andrew C., Redpath, Calum J., Norrie, John   +7 more
core   +5 more sources

Rare variants in NR2F2 cause congenital heart defects in humans [PDF]

, 2014
Congenital heart defects (CHDs) are the most common birth defect worldwide and are a leading cause of neonatal mortality. Nonsyndromic atrioventricular septal defects (AVSDs) are an important subtype of CHDs for which the genetic architecture is poorly ...
O'Kelly, Ita M., D’Alessandro, Lisa C.A., Mercer, Catherine L., Arndt, AK, Manickaraj, AK, Devriendt, K, Cosgrove, C., Bu'lock, Frances A, Mulder, B., Mital, Seema, Toka, Okan, Setchfield, Kerry, Lucassen, Anneke M., Mercer, C.L., Devriendt, Koenraad, Bentham, J., Arndt, Anne-Karin, Gewillig, M., O'Kelly, I.M., Siebert, Reiner, Breckpot, Jeroen, Hoff, K, Brook, J David, Fitzpatrick, David F, Mercer, CL, Hurles, Matthew E, Mercer, Catherine L, Schubert, Stephan, Salmon, Anthony P, Thienpont, Bernard, Manickaraj, A.K., Thornborough, C., Thienpont, B., FitzPatrick, David R., Hitz, Marc-Phillip, Lindsay, S, UK10K Consortium, Arndt, A.K., Gerety, Sebastian S, Bu'lock, FA, Setchfield, K, Mital, S., Siebert, R, Mulder, B, FitzPatrick, David F., O'Kelly, IM, Bu’Lock, Frances A., Watkins, H, Bentham, Jamie, Bhattacharya, Shoumo, Breckpot, J, Lucassen, AM, Swaminathan, G. Jawahar, Kramer, Hans-Heiner, Toka, O., Gewillig, M, Kramer, HH, Schubert, S., Salmon, AP, Al Turki, Saeed, Schubert, S, D'Alessandro, Lisa C. A., Brook, JD, Wilson, David I, Bhattacharya, S., Wilson, DI, Gerety, Sebastian S., Al Turki, S, Lindsay, Sarah, Devriendt, Koen, Breckpot, J., Hitz, MP, Watkins, H., Klaassen, Sabine, Salmon, Anthony P., Granados-Riveron, Javier, Harnack, C, Swaminathan, G Jawahar, Wilson, David I., Watkins, Hugh, Toka, O, Kramer, H.H., Abdul-Khaliq, H., O'Kelly, Ita M, Harnack, C., Wilson, D.I., Bu'lock, Frances A., Lucassen, A.M., Cosgrove, Catherine, Lucassen, Anneke M, Klaassen, S, Granados-Riveron, J, Low, J, Thornborough, Chris, D'Alessandro, LC, D'Alessandro, L.C.A., Low, J., Abdul-Khaliq, Hashim, Swaminathan, GJ, Gerety, S.S., Gewillig, Marc, Harnack, Christine, ?, ?, Al Turki, S., Lindsay, S., Hoff, K., Hurles, ME, D'Alessandro, Lisa C.A., Abdul-Khaliq, H, Mital, S, Klaassen, S., O’Kelly, Ita M., Granados-Riveron, J., Hurles, Matthew E., Salmon, A.P., Siebert, R., Fitzpatrick, D.F., Brook, J. David, Hitz, M.P., Fitzpatrick, DF, Thienpont, B, Mulder, Barbara, Swaminathan, G.J., Bu'Lock, F.A., Setchfield, K., Hurles, M.E., Gerety, SS, Cosgrove, C, Manickaraj, Ashok K, Devriendt, K., D'Alessandro, Lisa C A, Bhattacharya, S, Bentham, J, Manickaraj, Ashok K., Brook, J.D., Thornborough, C, Louw, Jacoba, Hoff, Kirstin, Low, Jacoba   +138 more
core   +1 more source

Atrial septal stenting - How I do it?

Annals of Pediatric Cardiology, 2015
A wide atrial communication is important to maintain hemodynamics in certain forms of congenital and acquired heart defects. In comparison to balloon septostomy or blade septostomy, atrial septal stenting provides a controlled, predictable, and long ...
Kothandam Sivakumar
doaj   +1 more source

Sox9 Expression in the Second Heart Field; A Morphological Assessment of the Importance to Cardiac Development with Emphasis on Atrioventricular Septation

Journal of Cardiovascular Development and Disease, 2022
Failure to form the septal structures that separate the left and right cardiac chambers results in defects that allow shunting of blood from one side of the heart to the other, leading to the mixing of oxygenated and de-oxygenated blood.
Raymond N. Deepe, Jenna R. Drummond, Renélyn A. Wolters, Emily A. Fitzgerald, Hannah G. Tarolli, Andrew B. Harvey, Andy Wessels   +6 more
doaj   +1 more source

O-linked β-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1.

PLoS Genetics, 2020
O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the only enzyme catalyzing O-GlcNAcylation. Although it has been shown that OGT plays an essential role in maintaining postnatal heart function, its role in heart development remains unknown ...
Yongxin Mu, Houzhi Yu, Tongbin Wu, Jianlin Zhang, Sylvia M Evans, Ju Chen   +5 more
doaj   +1 more source

Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times? [PDF]

, 2009
Chronic heart failure increases the risk of atrial fibrillation (AF), with the prevalence of AF paralleling the severity of heart failure.1 Factors that underlie this increased susceptibility to AF may include electrical, structural, and neurohumoral ...
Rankin, A.C., Workman, A.J.
core   +1 more source

The Congenital Malformation of the Interatrial Septum—A Review of Its Development and Embryology with Clinical Implications

Journal of Developmental Biology
The development process of the heart and cardiovascular system is fundamental in human development and highly regulated by genetic factors. This process needs to be highly regulated to prevent malformations.
Rui Caetano Oliveira, Paula Martins, Maria de Fátima Martins   +2 more
doaj   +1 more source

Simultaneous transcatheter closure of intralobar pulmonary sequestration and patent ductus arteriosus in a patient with infantile Scimitar syndrome

Türk Kardiyoloji Derneği Arşivi, 2015
Scimitar syndrome is a rare disease associated with a right lung sequestration vascularised by arteries arising from the abdominal aorta and abnormal venous drainage into the inferior vena cava. The infantile form is generally presented with severe heart
Eyup Aslan, Ibrahim Cansaran Tanidir, Murat Saygi, Sertac Hanedan Onan, Alper Guzeltas   +4 more
doaj   +1 more source

Three-dimensional trans-esophageal echocardiographic evaluation of atrial Septal defects : a pictorial essay [PDF]

, 2011
This pictorial assay illustrates the methodology of evaluating the atrial septal defects by three dimensional transesophageal echocardiography with the help of representative images.
Shrivastava, Sameer, Sharma, Vinay Kumar, Radhakrishnan, Sitaraman   +2 more
core  

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source