Results 61 to 70 of about 25,347 (189)

Effects of Intraoperative Ventilation Strategies on Ventilation Inhomogeneity and Inflammatory Response in Pediatric Cardiac Surgery—A Randomized Pilot Study

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Respiratory arrest during cardiopulmonary bypass (CPB) in pediatric cardiac surgery risks lung dysfunction including derecruitment, atelectasis, and inflammation. Continuous positive airway pressure (CPAP) and lung‐protective ventilation (LPV) during aortic cross‐clamping show inconsistent results in mitigating these risks.
Charlotte Billstein   +7 more
wiley   +1 more source

Cardiac conduction system and the electrocardiogram of the common hippopotamus (Hippopotamus amphibius)

open access: yesExperimental Physiology, EarlyView.
Abstract The common hippopotamus (Hippopotamus amphibius) shares a common terrestrial ancestor with whales (Cetacea) and has independently evolved similar physiological adaptations to their aquatic lifestyle. Although several studies have explored the electrical signalling in whale hearts, the understanding of the conduction system and electrical ...
Morten B. Thomsen   +12 more
wiley   +1 more source

Atrial fibrillation, sinoatrial and atrioventricular node dysfunction in a mouse model of heart failure with preserved ejection fraction

open access: yesExperimental Physiology, EarlyView.
Summary of the timeline of characterized events related to atrial fibrilation (AF) and diastolic dysfunction in a mouse heart failure with preserved ejection fraction (HFpEF) model. Three weeks after the initiation of the diet regimen with high fat diet (HFD) and Nω‐nitro‐l‐arginine methyl ester (l‐NAME) in drinking water to induce HFpEF, significantly
Bernadin Ndongson‐Dongmo   +2 more
wiley   +1 more source

Atrial Septal Defect and Percutaneous Closure: Healing the Heart From Within

open access: yesClinical Case Reports
ABSTRACTEarly diagnosis and percutaneous closure of symptomatic adult atrial septal defects can enhance cardiac function and relieve symptoms. Thorough pre‐procedural evaluation and diligent follow‐up care are essential for achieving the best outcomes and ensuring long‐term success.
Rikesh Acharya   +6 more
openaire   +2 more sources

The Expanding Clinical and Genetic Spectrum of Muscle Glycogen Storage Disease 0, (GSD0B)

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Glycogen storage disorders are a group of genetic disorders affecting glucose homeostasis in the body. Muscular glycogen stores are essential for liberating glucose for energy supply during bursts of activity and sustained muscle work. Muscle glycogen storage disease 0 (GSD0B) is associated with biallelic variants in GYS1 causing muscular ...
Sarah Donoghue   +16 more
wiley   +1 more source

AP2M1 Is a Candidate Gene for Microcephaly and Intellectual Disability in 3q27.1 Deletions

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Deletions of the 3q26.33q27.2 region appear to correlate with a distinct phenotype, although there are few reported cases. Here, we present seven previously unreported individuals carrying de novo 3q27 deletions (under 5 Mb), which include the AP2M1 (adaptor‐related protein complex 2, mu‐1 subunit) gene and summarize data from 12 previously ...
Russell Gear   +16 more
wiley   +1 more source

MRI Assessment of Energy Loss Within the Thoracic Aorta and Its Impact on Cardiac Function in Fontan Patients After Aortic Reconstruction

open access: yesJournal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1397-1407, November 2025.
ABSTRACT Background In Fontan patients undergoing aortic reconstruction, concerns regarding the impact of aortic function on ventricular function exist. Purpose 4D Flow MRI was used to compare energy loss (EL) within the thoracic aorta in patients with and without aortic reconstruction. Study Type Retrospective case control.
Yujiro Ide   +4 more
wiley   +1 more source

Transcaval Transcatheter Aortic Valve Replacement: Clinical Outcomes From a TAVI Program Without Prior Transcaval Experience

open access: yesCatheterization and Cardiovascular Interventions, Volume 106, Issue 4, Page 2592-2600, October 1, 2025.
ABSTRACT Background Despite the emergence of the transcaval (TCv) access route for transcatheter aortic valve implantation (TAVI) in the treatment of patients with hostile iliofemoral anatomy, the number of patients reported in clinical series of TCv TAVI has been relatively small (< 500 published cases). We assessed procedural and clinical outcomes in
Conor J. Doyle   +6 more
wiley   +1 more source

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