Results 91 to 100 of about 36,230 (243)

Perioperative Management for Patients With Spinal Muscular Atrophy Undergoing Scoliosis Surgery: A Single‐Center Retrospective Study

Orthopaedic Surgery, EarlyView.
This largest Asian case series confirms that posterior spinal fusion for SMA scoliosis is safe and effective despite severe deformity and markedly impaired pulmonary function. Meticulous multidisciplinary care, including advanced airway planning, hemodynamic support, blood management, and proactive electrolyte correction, is critical to optimizing ...
Ai Hu, Xiuhua Zhang, Lulu Ma, Haisong Lu, Yulei Dong, Weiyun Chen, Yuguang Huang, Jianxiong Shen   +7 more
wiley   +1 more source

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni, Corrado Poggesi, Cecilia Ferrantini   +2 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

CONGENITAL HEART BLOCK WITH ATRIAL AND VENTRICULAR SEPTAL DEFECT [PDF]

Heart, 1943
openaire   +4 more sources

The detailed profile of congenital heart diseases in 254 children with Down syndrome in Saudi Arabia

The Cardiothoracic Surgeon
Background Down syndrome is the most common chromosomal abnormality in humans. It is associated with several congenital anomalies, including a spectrum of congenital heart diseases.
Naif Alkhushi
doaj   +1 more source

Elevational variation in heart mass and suppression of hypoxia‐induced right ventricle hypertrophy in Andean leaf‐eared mice (Phyllotis)

The Journal of Physiology, EarlyView.
Abstract figure legend In lowland mammals that ascend to high elevation, hypoxia‐induced changes in the pulmonary circulation can give rise to hypoxic pulmonary hypertension (HPH) and associated right‐ventricle (RV) hypertrophy. Andean mice with broad elevational ranges have greater heart mass relative to body size at higher elevations, but they ...
Naim M. Bautista, Nathanael D. Herrera, Marcial Quiroga‐Carmona, Chandrasekhar Natarajan, Adriana Rico‐Cernohorska, Jorge Salazar Bravo, Graham R. Scott, Guillermo D'Elía, Zachary A. Cheviron, Jay F. Storz   +9 more
wiley   +1 more source

Congenital Heart Diseases: Tetralogy of Fallot, Atrial Septal Defect, and Ventricular Septal Defect

Congenital heart diseases (CHDs) represent structural abnormalities of the heart present at birth. This article provides a comprehensive overview of three common CHDs: Tetralogy of Fallot (TOF), Atrial Septal Defect (ASD), and Ventricular Septal Defect (VSD).
Abdiraimov Isakender, Safeeria Hussain Fiza Mehar, Sunil Sony, Sharafudheen Fiya Fathima   +3 more
openaire   +1 more source

Surgical Ventricular Septal Defect Repair

JACC: Case Reports
Ventricular septal defects (VSDs), the most common of congenital heart defects, vary widely in anatomy and size. Surgical treatment of very large VSDs can be challenging because no clear recommendations exist about which defects can undergo biventricular
Emmanuelle Fournier, MD, Bastien Provost, MD, Alice Dirickx, MD, Estibaliz Valdeolmillos, MD, Gregoire Albenque, MD, Clément Batteux, MD, Viktoria Weixler, MD, PhD, Sébastien Hascöet, MD, PhD, Emre Belli, MD, PhD   +8 more
doaj   +1 more source

Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1608-1618, July 2026.
ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio, Martina Caiazza, Emanuele Monda, Giustina Aruta, Alberto Budillon, Augusto Esposito, Adelaide Fusco, Annapaola Cirillo, Marta Rubino, Immacolata Viscovo, Gioacchino Scarano, Matteo Della Monica, Vincenzo Nigro, Giulio Piluso, Leandro Pecchia, Maria Giovanna Russo, Giuseppe Limongelli   +16 more
wiley   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source