Results 121 to 130 of about 2,163,869 (277)

Vertical Right Axillary Thoracotomy for Repair of Ventricular Septal Defects in Infants and Children: Experience with 50 Consecutive Cases

open access: yesJournal of Cardiovascular Development and Disease
Objectives: Recently, there has been a growing interest in repairing congenital heart defects in children via right axillary thoracotomy. We sought to review our experience with ventricular septal defect closure through this approach.
Yasin Essa   +5 more
doaj   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley   +3 more
wiley   +1 more source

Understanding the role of Shroom3 in the developing mouse myocardium.

open access: yesPLoS ONE
Loss of actin cytoskeleton control can hinder integral developmental and physiological processes and can be the basis for a subset of developmental defects.
Jennifer L Carleton   +6 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

Congenital Heart Diseases: Tetralogy of Fallot, Atrial Septal Defect, and Ventricular Septal Defect

open access: yes
Congenital heart diseases (CHDs) represent structural abnormalities of the heart present at birth. This article provides a comprehensive overview of three common CHDs: Tetralogy of Fallot (TOF), Atrial Septal Defect (ASD), and Ventricular Septal Defect (VSD).
Abdiraimov Isakender   +3 more
openaire   +1 more source

Chapter: imaging of atrial and ventricular septal defects

open access: yes, 2022
Septal defects together account for the majority of the congenital heart defects (CHD); these can occur in isolation or associated with other CHDs. Hemodynamic manifestations are dependent upon the size, location, and the number of the defects, along ...
Uppu, Santosh C.
core  

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni   +2 more
wiley   +1 more source

Multiple Muscular Ventricular Septal Defects: Use of Fluorescein Dye to Identify Residual Defects

open access: yes, 2014
Multiple muscular ventricular septal defects remain a challenge for the congenital heart surgeon. The optimal strategy for an infant or neonate with multiple muscular ventricular septal defects is still unclear.
Kundan, S   +5 more
core   +1 more source

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