Results 21 to 30 of about 53,437 (286)

Prevalence of congenital septal defects among congenital heart defect patients in East Africa: A systematic review and meta-analysis.

PLoS ONE, 2021
IntroductionCongenital heart defects (CHDs) are the most common congenital defects and accounts for nearly one-third of all major congenital anomalies. It is the leading causes of birth defect-associated morbidity, mortality, and medical expenditures. Of
Yossef Teshome Zikarg, Chalachew Tiruneh Yirdaw, Teshome Gebremeskel Aragie   +2 more
doaj   +1 more source

Patient with Ebstein anomaly and Down syndrome. Strange combination

Acta Pediátrica de México, 2014
The most common congenital heart diseases in children with Down syndrome are atrial or ventricular septal defects, patent ductus arteriosus or endocardial cushion defects.
Jesús de Rubens-Figueroa, Bruno Marino   +1 more
doaj   +1 more source

Altered Cerebral Microstructure in Adults With Atrial Septal Defect and Ventricular Septal Defect Repaired in Childhood

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Delayed brain development, brain injury, and neurodevelopmental disabilities are commonly observed in infants operated for complex congenital heart defect. Our previous findings of poorer neurodevelopmental outcomes in individuals operated for
Benjamin Asschenfeldt, Lars Evald, Camilla Salvig, Johan Heiberg, Leif Østergaard, Simon Fristed Eskildsen, Vibeke Elisabeth Hjortdal   +6 more
doaj   +1 more source

Shunt quantification in congenital heart disease based on two-dimensional speckle tracking [PDF]

, 2012
In this work we investigated how high frame rate speckle tracking based on plane wave imaging could be used to improve the quantification of peak velocities in shunt flows due to septal defects.
Fadnes, Solveig, Lovstakken, Lasse, Nyrnes, Siri Ann, Swillens, Abigail, Torp, Hans   +4 more
core   +2 more sources

Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]

, 2016
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M, Field, Michael E, Hayes, Kevin, Hoffmayer, Kurt S, Scheinman, Melvin M   +4 more
core   +2 more sources

Transcatheter closure of Ventricular Septal defects in Malta : initial experience [PDF]

, 2005
Ventricular septal defects (VSD) consist of deficiencies of the wall separating the two ventricles. VSDs are the commonest congenital cardiac defects. Small VSDs rarely require intervention, however, larger defects cause ventricular volume overload with ...
Aquilina, Oscar, DeGiovanni, Joseph V., Fenech, Albert, Formosa Gouder, Mireille, Grech, Victor E., Magic, Jadran, Manche, Alexander   +6 more
core  

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Genetic Insights into Congenital Cardiac Septal Defects—A Narrative Review

Biology
Congenital heart diseases (CHDs) are a group of complex diseases characterized by structural and functional malformations during development in the human heart; they represent an important problem for public health worldwide.
Jorge L. Cervantes-Salazar, Nonanzit Pérez-Hernández, Juan Calderón-Colmenero, José Manuel Rodríguez-Pérez, María G. González-Pacheco, Clara Villamil-Castañeda, Angel A. Rosas-Tlaque, Diego B. Ortega-Zhindón   +7 more
doaj   +1 more source

Sox9 Expression in the Second Heart Field; A Morphological Assessment of the Importance to Cardiac Development with Emphasis on Atrioventricular Septation

Journal of Cardiovascular Development and Disease, 2022
Failure to form the septal structures that separate the left and right cardiac chambers results in defects that allow shunting of blood from one side of the heart to the other, leading to the mixing of oxygenated and de-oxygenated blood.
Raymond N. Deepe, Jenna R. Drummond, Renélyn A. Wolters, Emily A. Fitzgerald, Hannah G. Tarolli, Andrew B. Harvey, Andy Wessels   +6 more
doaj   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source