Results 101 to 110 of about 134,709 (312)

Septation of the Intrapericardial Arterial Trunks in the Early Human Embryonic Heart

Chinese Medical Journal, 2018
Background: Outflow tract (OFT) septation defects are a common cause of congenital heart disease. Numerous studies have focused on the septation mechanism of the OFT, but have reported inconsistent conclusions. This study, therefore, aimed to investigate
Yan-Ping Yang, Hai-Rong Li, Xi-Mei Cao, Cong-Jin Qiao, Jing Ya   +4 more
doaj   +1 more source

PERFORATION OF THE INTERVENTRICULAR SEPTUM OF THE HEART [PDF]

Archives of Internal Medicine, 1921
Perforation of the interventricular septum of the heart, aside from cases of congenital malformation, in the great majority of cases is due either' to rupture of an interventricular aneurysm or to ulcerative endocarditis. Perforation from other causes, such as rupture of a hydatid cyst, 1 has been described but such cases are relatively very rare ...
openaire   +1 more source

Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio, Martina Caiazza, Emanuele Monda, Giustina Aruta, Alberto Budillon, Augusto Esposito, Adelaide Fusco, Annapaola Cirillo, Marta Rubino, Immacolata Viscovo, Gioacchino Scarano, Matteo Della Monica, Vincenzo Nigro, Giulio Piluso, Leandro Pecchia, Maria Giovanna Russo, Giuseppe Limongelli   +16 more
wiley   +1 more source

Generation of iPSC from cardiac and tail-tip fibroblasts derived from a second heart field reporter mouse

Stem Cell Research, 2016
Mef2c Anterior Heart Field (AHF) enhancer is activated during embryonic heart development and it is expressed in multipotent cardiovascular progenitors (CVP) giving rise to endothelial and myocardial components of the outflow tract, right ventricle and ...
Javier Linares, Estibaliz Arellano-Viera, Olalla Iglesias-García, Carmen Ferreira, Elena Iglesias, Gloria Abizanda, Felipe Prósper, Xonia Carvajal-Vergara   +7 more
doaj   +1 more source

Early postoperative interventional ASD-closure for severe atrial right to left shunt in a neonate with common arterial trunk [PDF]

, 2013
Although closure of an atrial septal defect (ASD II) with an occluding device in the first year of life is not a routine procedure, it is a feasible treatment, even in neonates.
Dilber, Daniel, Eicken, Andreas, Hess, John   +2 more
core   +1 more source

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12‐Related Developmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

Left ventricular clefts - incidental finding or pathologic sign of Wilson's disease? [PDF]

, 2019
Background: Wilson’s disease is an inherited autosomal recessive multi-systemic disorder characterized by reduced excretion and consequently excessive accumulation of copper in different organs, such as the heart. Results: In a prospective controlled
Christoph, Marian, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Pieske, Burkert, Quick, Silvio, Reuner, Ulrike, Speiser, Uwe, Weidauer, Marie, Zhang, Kun   +9 more
core   +1 more source

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source

Central extracorporeal membrane oxygenation as a bridge to decision in a patient with a ventricular septal rupture complicating a myocardial infarction

Revista Colombiana de Cardiología, 2018
In the era of primary percutaneous coronary intervention, mechanical complications after acute myocardial infarction are extremely rare, with an incidence of less than 0.5%. Rupture of the ventricular septum is the least frequent occurrence.
Eduardo Josué Flores-Umanzor, Margarida Pujol-Lopéz, Victoria Martin, Rut Andrea, Marta Farrero   +4 more
doaj   +1 more source

Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]

, 2016
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite, Cardelli, Patrizia, Celic, Vera, Di Somma, Salvatore, Escribano, Elena, Floridi, Federico, Lopez-Andres, Natalia, Magrini, Laura, Majstorovic, Anka, Marino, Rossella, Melero, Amaia, Pencic-Popovic, Biljana, Roy, Ignacio, Salerno, Gerardo, Sljivic, Aleksandra   +14 more
core   +1 more source