Results 61 to 70 of about 2,286,837 (350)

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Lipomatous hypertrophy of the atrial septum – a benign heart anomaly causing unexpected surgical problems: a case report

BMC Cardiovascular Disorders, 2018
Background Lipomatous hypertrophy of the atrial septum (LHAS) is an anomaly of the heart. It is characterized by an infiltration of adipocytes into myocytes of the interatrial septum, sparing the fossa ovalis, which gives a characteristic hourglass ...
Grzegorz Bielicki, Marceli Lukaszewski, Kinga Kosiorowska, Jacek Jakubaszko, Rafal Nowicki, Marek Jasinski   +5 more
doaj   +1 more source

Angiography‐guided mid/high septal implantation of ventricular leads in patients with congenital heart disease

Journal of Arrhythmia, 2021
Background Conduction system pacing prevents pacing‐induced cardiomyopathy, but it can be challenging to perform in patients with congenital heart disease (CHD), and mid/high septal lead implantation is an alternative.
Jayaprakash Shenthar, Sanjai P. Valappil, Maneesh K. Rai, Bharatraj Banavalikar, Deepak Padmanabhan, Tammo Delhaas   +5 more
doaj   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

Crisscross heart with dextrocardia and intact interventricular septum

Annals of Pediatric Cardiology, 2014
Crisscross heart is a rare congenital heart disease characterized by a twisted atrioventricular connection, as a result of rotation of the ventricular mass along its long axis.
P Kader Muneer, Sajeer Kalathingathodika, Govindan Sajeev Chakanalil, Manuel M Sony   +3 more
doaj   +1 more source

Comparison of regional blood flow values measured by radioactive and fluorescent microspheres [PDF]

, 2002
Fluorescent microspheres (FM) have become an attractive alternative to radioactive microspheres (RM) for the measurement of regional blood flow (RBF). The aim of the present study was to investigate the comparability of both methods by measuring RBF with
Habler, O., Harris, A. G., Kleen, M., Meisner, F., Messmer, K., Raab, S., Thein, E.   +6 more
core   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Specialized impulse conduction pathway in the alligator heart

eLife, 2018
Mammals and birds have a specialized cardiac atrioventricular conduction system enabling rapid activation of both ventricles. This system may have evolved together with high heart rates to support their endothermic state (warm-bloodedness) and is ...
Bjarke Jensen, Bastiaan J Boukens, Dane A Crossley II, Justin Conner, Rajiv A Mohan, Karel van Duijvenboden, Alex V Postma, Christopher R Gloschat, Ruth M Elsey, David Sedmera, Igor R Efimov, Vincent M Christoffels   +11 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Detailed structural assessment of healthy interventricular septum in the presence of remodeling infarct in the free wall – A finite element model

Heliyon, 2019
Purpose: Computational modelling may improve the fundamental understanding of various mechanisms of diseases more particularly related to clinical challenges.
Fulufhelo Nemavhola
doaj   +1 more source