Results 61 to 70 of about 87,571 (310)

Detailed structural assessment of healthy interventricular septum in the presence of remodeling infarct in the free wall – A finite element model

open access: yesHeliyon, 2019
Purpose: Computational modelling may improve the fundamental understanding of various mechanisms of diseases more particularly related to clinical challenges.
Fulufhelo Nemavhola
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng   +10 more
wiley   +1 more source

The caveats in the diagnosis of anomalous origin of left coronary artery from pulmonary artery (ALCAPA) [PDF]

open access: yes, 2010
Anomalous origin of left coronary artery from pulmonary artery (ALCAPA) is an infrequent, well described, but important anomaly of the coronary origin. Early diagnosis and prompt surgical treatment of the disease can be life saving. However, there are
Varghese, M.J., Kothari, Shyam S.
core  

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun   +10 more
wiley   +1 more source

Double orifice mitral valve associated with Ventricular Septal Defect in an infant : case report [PDF]

open access: yes, 2011
Double orifice mitral valve (DOMV) is an uncommon anomaly characterized by a mitral valve with a single fibrous annulus with two orifices opening into the left ventricle.
Taksande, Amar M.   +2 more
core  

Pulmonary Atresia with Intact Ventricular Septum in a Neonate

open access: yes, 2018
Introduction: Pulmonary atresia with an intact ventricular septum is a condition that is characterized by a complete obstruction to right ventricular outflow with varying degrees of right ventricular and tricuspid valve hypoplasia.
Raymond Pranata   +5 more
core   +1 more source

Characterization of the Interventricular Septum Development

open access: yes, 2020
The interventricular septum (IVS) separates the right and left ventricles of the heart, preventing the mixing of blood from the oxygenated systemic circulation with that of the deoxygenated pulmonary circulation.
Santana-Bueno, Vivi Diana
core   +1 more source

Influence of Football on Physiological Cardiac Indexes in Professional and Young Athletes

open access: yesFrontiers in Physiology, 2018
Background: After long-term intensive training, considerable morphological and functional heart changes occur in professional athletes. Such changes arise progressively and regress upon interruption of the physical activity.
Cristian V. Francavilla   +17 more
doaj   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

open access: yesAdvanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu   +12 more
wiley   +1 more source

Three-dimensional trans-esophageal echocardiographic evaluation of atrial Septal defects : a pictorial essay [PDF]

open access: yes, 2011
This pictorial assay illustrates the methodology of evaluating the atrial septal defects by three dimensional transesophageal echocardiography with the help of representative images.
Shrivastava, Sameer   +2 more
core  

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